Monocyclic Sesquiterpenes

Sesquiterpene compounds that contain a single ring structure.

Also Known As:

Derivative, Bisabolane; Derivative, Cyclofarnesane; Derivative, Elemane; Derivative, Humalane; Derivatives, Bisabolane; Derivatives, Cyclofarnesane; Derivatives, Elemane; Derivatives, Humalane; Sesquiterpene, Monocyclic; Sesquiterpenes, Monocyclic; Bisabolane; Bisabolane Derivative; Bisabolane Derivatives; Bisabolanes; Cyclofarnesane; Cyclofarnesane Derivative; Cyclofarnesane Derivatives; Cyclofarnesanes; Elemane; Elemane Derivative; Elemane Derivatives; Elemanes; Humalane; Humalane Derivative; Humalane Derivatives; Humalanes; Monocyclic Sesquiterpene

Networked: 14 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Monocyclic Sesquiterpenes: 14
        Abscisic Acid: 929
        bisabolol: 95
        humulene: 25
        zingiberene: 13
        beta-bisabolene: 1
        Germacrane Sesquiterpenes: 1
        (6R,7S,11R,10S)-15-hydroxy-sesquisabinene hydrate
        2,3-cyclopropanated abscisic acid
        7-epi-sesquithujene
        bisabolol acetate
        bisabololoxide B
        elemane aldehyde
        prenyl-alpha-elemenone

Experts

1.	Wang, Qin: 2 articles (12/2008 - 09/2007)
2.	Adrian, Thomas E: 1 article (01/2022)
3.	Almarzooqi, Saeeda: 1 article (01/2022)
4.	Attoub, Samir: 1 article (01/2022)
5.	Bhongade, Bhoomendra A: 1 article (01/2022)
6.	Dudeja, Pradeep K: 1 article (01/2022)
7.	Ojha, Shreesh K: 1 article (01/2022)
8.	Patil, Rajesh B: 1 article (01/2022)
9.	Raj, Vishnu: 1 article (01/2022)
10.	Subramanya, Sandeep B: 1 article (01/2022)

Related Diseases

1.	Colitis 09/01/2021 - "In the present study, the effect of nerolidol (NRD), a monocyclic sesquiterpene found in German Chamomile tea, was investigated in acetic acid-induced colitis model in Wistar rats. "
2.	Neoplasms (Cancer) 01/16/2019 - "In a bioassay, the bisabolane-type sesquiterpenoids 8, 10, and 11 exhibited cytotoxicity against several human cancer cell lines." 09/01/2008 - "In the course of our screening for a new anti-tumor substance, the bisabolane sesquiterpenoid endoperoxide, 3,6-epidioxy-1,10-bisaboladiene (EDBD), was isolated from the edible wild-plant, Cacalia delphiniifolia. " 09/01/2008 - "The bisabolane sesquiterpenoid endoperoxide, 3,6-epidioxy-1,10-bisaboladiene, isolated from Cacalia delphiniifolia inhibits the growth of human cancer cells and induces apoptosis." 01/01/2020 - "Germacrone, a monocyclic sesquiterpene, exerts marked antitumor effects in a variety of cancers, including hepatocellular carcinoma, gastric cancer, and breast cancer. "
3.	Hepatocellular Carcinoma (Hepatoma) 12/01/2008 - "Redifferentiation of human hepatoma cells (SMMC-7721) induced by two new highly oxygenated bisabolane-type sesquiterpenes." 09/01/2007 - "A bisabolane sesquiterpene, rel-(1S,4R,5S,6R)-4,5-diacetoxy-6- [(R)-5-hydroxy-1,5-dimethylhex-3-enyl]- 3-methylcyclohex-2-enyl (Z)-2-methylbut-2 -enoate, which was newly isolated from the roots of Leontopodium longifolium, presented specific anticancer activity against human leukemia HL-60 cells, but did not inhibit proliferation of human hepatoma SMMC-7721 cells and human normal hepatocytes L02 cells. " 01/01/2020 - "Germacrone, a monocyclic sesquiterpene, exerts marked antitumor effects in a variety of cancers, including hepatocellular carcinoma, gastric cancer, and breast cancer. "
4.	Inflammation (Inflammations) 01/01/2022 - "Here, we investigated the anti-inflammatory effects of α-bisabolol, a naturally occurring monocyclic sesquiterpene alcohol present in many aromatic plants, in colonic inflammation. " 01/01/2023 - "Turmeronols (A and B), bisabolane-type sesquiterpenoids found in turmeric, reduce inflammation outside the brain in animals; however, their effects on neuroinflammation, a common pathology of various neurodegenerative diseases, are not understood. "
5.	Acute Pain 03/12/2010 - "(-)-alpha-Bisabolol is an unsaturated monocyclic sesquiterpene alcohol found as the major constituent of many essential oils, like the German chamomile (Chamomilla recutita (L.) Rauschert), a plant reported to reduce the perception of acute pain and used for centuries for their medicinal properties. "

Related Drugs and Biologics

1.	Acetic Acid (Vinegar)
2.	Tea
3.	nerolidol
4.	Sesquiterpenes
5.	bisabolol (levomenol)
6.	Volatile Oils (Essential Oils)
7.	Nitroblue Tetrazolium
8.	Antiviral Agents (Antivirals)
9.	3,6-epidioxy-1,10-bisaboladiene
10.	zerumbone

Related Therapies and Procedures

1.	Microspheres (Microsphere)