poly(hydroxyethyl methacrylate-co-styrene sulfonate)

binds gluten

Also Known As:

P(HEMA-co-SS); poly(HEMA-co-SS)

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
Macromolecular Substances: 97
- Polymers: 13051
  - Plastics: 13104
    - Polystyrenes: 897
      - poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3
    - Synthetic Resins: 101
      - Acrylic Resins: 282
        Polymethacrylic Acids
        Polyhydroxyethyl Methacrylate: 110
        poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3
  - Polyethylene Glycols: 3865
    - Polyhydroxyethyl Methacrylate: 110
      - poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3
Biomedical and Dental Materials
- Polymers: 13051
  - Plastics: 13104
    - Polystyrenes: 897
      - poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3
    - Synthetic Resins: 101
      - Acrylic Resins: 282
        Polymethacrylic Acids
        Polyhydroxyethyl Methacrylate: 110
        poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3
  - Polyethylene Glycols: 3865
    - Polyhydroxyethyl Methacrylate: 110
      - poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - Plastics: 13104
        Polystyrenes: 897
        poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3
        Synthetic Resins: 101
        Acrylic Resins: 282
        Polymethacrylic Acids
        Polyhydroxyethyl Methacrylate: 110
        poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3
      - Polyethylene Glycols: 3865
        Polyhydroxyethyl Methacrylate: 110
        poly(hydroxyethyl methacrylate-co-styrene sulfonate): 3

Experts

1.	Leroux, Jean-Christophe: 2 articles (02/2012 - 02/2009)
2.	Pinier, Maud: 2 articles (02/2012 - 02/2009)
3.	Lupan, Iulia: 1 article (01/2013)
4.	Samaşca, Gabriel: 1 article (01/2013)
5.	Sur, Genel: 1 article (01/2013)
6.	David, Chella S: 1 article (02/2012)
7.	Drasarova, Hana: 1 article (02/2012)
8.	Fuhrmann, Gregor: 1 article (02/2012)
9.	Galipeau, Heather J: 1 article (02/2012)
10.	Murray, Joseph A: 1 article (02/2012)

Related Diseases

1.	Celiac Disease (Celiac Sprue) 01/01/2013 - "As such new therapies, like TG2 inhibitors, the copolymer P (HEMA-co-SS) and other new experimental therapies, have emerged in celiac disease. " 02/01/2012 - "Furthermore, incubation of P(HEMA-co-SS) with mucosal biopsy specimens from patients with celiac disease showed that secretion of tumor necrosis factor-α was reduced in the presence of partially digested gliadin. " 02/01/2012 - "P(HEMA-co-SS) reduced digestion of wheat gluten and barley hordein in vitro, thereby decreasing formation of toxic peptides associated with celiac disease. " 02/01/2009 - "The influence of the polymer on protein structure was weaker at neutral than acidic pH. Interaction with poly(HEMA-co-SS) disrupted alpha-gliadin conformation and self-association to form new complex particles at neutral pH. This study provides insight into the mechanism of poly(HEMA-co-SS)/alpha-gliadin interaction and the polymer as alpha-gliadin sequestering agents in the supportive treatment of celiac disease."
2.	Inflammation (Inflammations) 02/01/2012 - "After oral administration to rodents, P(HEMA-co-SS) was predominantly excreted in feces, even in the presence of low-grade mucosal inflammation and increased intestinal permeability. "

Related Drugs and Biologics

1.	Gliadin
2.	Sequestering Agents
3.	Proteins (Proteins, Gene)
4.	Polymers
5.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6.	Peptides (Polypeptides)
7.	Glutens (Glutelin)

Related Therapies and Procedures

1.	Investigational Therapies (Experimental Therapy)
2.	Therapeutics
3.	Oral Administration