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3- ((6- (ethylsulfonyl)- 3- pyridinyl)oxy)- 5- (2- hydroxy- 1- methylethoxy)- N- (1- methyl- 1H- pyrazol- 3- yl)benzamide

a glucokinase activator; structure in first source

Also Known As:

MK 0941; MK-0941; MK0941

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Alba, Maria: 1 article (12/2011)
2.	Amin, Himal: 1 article (12/2011)
3.	Berger, Joel P: 1 article (12/2011)
4.	Chiba, Masato: 1 article (12/2011)
5.	Davies, Michael J: 1 article (12/2011)
6.	Eiki, Jun-ichi: 1 article (12/2011)
7.	Fujii, Kenji: 1 article (12/2011)
8.	Futamura, Mayumi: 1 article (12/2011)
9.	Goldstein, Barry J: 1 article (12/2011)
10.	Goto-Shimazaki, Hiroko: 1 article (12/2011)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 12/01/2011 - "These findings support further investigation of MK-0941 as a potential therapeutic agent for treatment of type 2 diabetes." 12/01/2011 - "Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs." 12/01/2011 - "To assess the efficacy and safety of MK-0941, a glucokinase activator (GKA), when added to stable-dose insulin glargine in patients with type 2 diabetes. " 12/01/2011 - "Effects of MK-0941, a novel glucokinase activator, on glycemic control in insulin-treated patients with type 2 diabetes."
2.	Hypoglycemia (Reactive Hypoglycemia) 12/01/2011 - "MK-0941 was associated with an increased incidence of hypoglycemia and elevations in triglycerides and blood pressure." 12/01/2011 - "MK-0941 at one or more doses was associated with significant increases in the incidence of hypoglycemia, triglycerides, systolic blood pressure, and proportion of patients meeting criteria for predefined limits of change for increased diastolic blood pressure. "

Related Drugs and Biologics

1.	Glucokinase
2.	Triglycerides (Triacylglycerol)
3.	Insulin (Novolin)
4.	Insulin Glargine (Lantus)

Related Therapies and Procedures

1.	Glycemic Control