Imperforate Hymen

A hereditary austosomal recessive condition characterized by an imperforate hymen and AMENORRHEA. HEMATOCOLPOS or HYDROCOLPOS may also be present but internal and external genitalia are usually normal. OMIM: 237100

Also Known As:

Networked: 20 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Hydrocolpos
2.	Pelvic Pain
3.	Pathologic Constriction (Stenosis)
4.	Polyps
5.	Hydronephrosis

Experts

1.	Aoun, Bilal: 1 article (05/2022)
2.	Chouikh, Taieb: 1 article (05/2022)
3.	Degheili, Jad A: 1 article (05/2022)
4.	Khaled, Mohamed: 1 article (05/2022)
5.	Acar, Ali: 1 article (04/2021)
6.	Alan, Cemre: 1 article (04/2021)
7.	Balci, Osman: 1 article (04/2021)
8.	Elçi Atılgan, Adeviye: 1 article (04/2021)
9.	Ercan, Fedi: 1 article (04/2021)
10.	Niftiyev, Kemal: 1 article (04/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Imperforate Hymen:

1.	Estrogens (Estrogen)FDA Link 11/01/2008 - "Rarely, obstetric sonography may prenatally detect imperforate hymen due to presentation of hydrocolpos or hydrometrocolpos in the fetus if fetal cervical and vaginal secretions accumulate in response to circulating maternal estrogens. " 01/01/2008 - "Her normal menstrual cycle at age 12 not only excluded a mullerian abnormality or imperforate hymen but led to speculation as to whether anovulatory bleeding from unopposed estrogen was possible but that somehow the presence of P inhibited the endometrial shedding process. "
2.	Tumor Biomarkers (Tumor Markers)IBA 01/01/2013 - "To report the clinical characteristics of 14 patients with imperforate hymen and their levels of tumor markers (CA 19-9 and CA 125). "
3.	Hyaluronic Acid (Hyaluronan)IBA 06/01/2009 - "Use of hyaluronic acid for vaginal stenosis in a woman with a history of imperforate hymen and transverse vaginal septum: a case report."
4.	EnzymesIBA 06/01/2010 - "This clinical case is the only one that we have found in the current literature where congenital imperforate hymen accompanied with hematocolpos is associated with renal obstruction in combination with polyhydramnios and increase in maternal steroidogenic enzymes." 06/01/2010 - "Congenital imperforate hymen with hydrocolpos and hydronephrosis associated with severe hydramnios and increase of maternal ovarian steroidogenic enzymes."
5.	AndrogensIBA 10/01/2022 - "The differential diagnosis includes congenital vaginal agenesis, low transverse vaginal septum, androgen insensitivity, and imperforate hymen. "
6.	antineoplaston A10 (A 10)IBA 11/01/1997 - "A review article in 1891 reported a 10% mortality rate associated with treatment of the imperforate hymen. "

Therapies and Procedures

1.	Decompression 12/01/2023 - "Whether hydrometrocolpos is due to an isolated condition like imperforate hymen, a complex abnormality like cloacal malformation, or a part of a large congenital syndrome, the mainstay of treatment is decompression of the dilated vagina and surgical correction of the outflow obstruction. "
2.	Catheters 03/01/2008 - "The treatment of 65 women with imperforate hymen by a central incision and application of Foley catheter and accompanying commentary." 11/01/2007 - "The treatment of 65 women with imperforate hymen by a central incision and application of Foley catheter." 01/10/2003 - "After performed oval-centralize closure on imperforate hymen membranes, Foley catheter was inserted through closure of hymen and then balloon of Foley catheter was insufflated 10 cm(3). " 01/10/2003 - "Treatment of imperforate hymen by application of Foley catheter." 01/10/2003 - "Treatment of imperforate hymen by application of Foley catheter."
3.	Gas Lasers 08/01/1989 - "A method for the management of imperforate hymen using carbon dioxide laser is described. " 08/01/1989 - "Management of imperforate hymen with the carbon dioxide laser." 08/01/1989 - "In four patients presenting with imperforate hymen, the hymen was excised by CO2 laser under local anesthesia. " 01/01/2015 - "In this observational study, we enrolled 49 women who underwent CO2 laser surgery for the following indications: Bartholin's gland cyst, imperforate hymen, vaginal septum, Nabothian cyst, and vaginal polyps. "
4.	Stents 09/01/2020 - "However, 50 days after surgery, pyocolpos due to imperforate hymen and vestibulovaginal stenosis were diagnosed and surgically corrected, and the ureteral stent was removed because the ureter had completely healed. "
5.	Sutures (Suture) 01/01/2015 - "Imperforate hymen presenting with fecal frequency and use of stay sutures at time of hymenectomy. "