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4,4',6,7,7',8- hexahydroxy- 1,1'- dimethoxy- 6',7- dimethyl- 5,6,7,8- tetrahydro- (2,2'- bianthracene)- 9,9',10,10'- tetraone

has antineoplastic activity; isolated from the mangrove endophytic fungus Alternaria; structure in first source

Also Known As:

alterporriol L

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Anthracenes: 12
        Anthrones: 12
        Anthraquinones: 788
        4,4',6,7,7',8-hexahydroxy-1,1'-dimethoxy-6',7-dimethyl-5,6,7,8-tetrahydro-(2,2'-bianthracene)-9,9',10,10'-tetraone: 1
- Quinones: 434
  - Anthraquinones: 788
    - 4,4',6,7,7',8-hexahydroxy-1,1'-dimethoxy-6',7-dimethyl-5,6,7,8-tetrahydro-(2,2'-bianthracene)-9,9',10,10'-tetraone: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Anthracenes: 12
    - Anthrones: 12
      - Anthraquinones: 788
        4,4',6,7,7',8-hexahydroxy-1,1'-dimethoxy-6',7-dimethyl-5,6,7,8-tetrahydro-(2,2'-bianthracene)-9,9',10,10'-tetraone: 1

Experts

1.	Cai, Jiye: 1 article (01/2012)
2.	Chen, Bin: 1 article (01/2012)
3.	Huang, Caihuan: 1 article (01/2012)
4.	Jin, Hua: 1 article (01/2012)
5.	Lin, Yongcheng: 1 article (01/2012)
6.	Lu, Yongjun: 1 article (01/2012)
7.	Song, Bing: 1 article (01/2012)
8.	Zhao, Hongxia: 1 article (01/2012)
9.	Zhu, Xun: 1 article (01/2012)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2012 - "Moreover, the alterporriol L could induce cancer cell apoptosis or necrosis. "
2.	Necrosis 01/01/2012 - "Moreover, the alterporriol L could induce cancer cell apoptosis or necrosis. "
3.	Breast Neoplasms (Breast Cancer) 01/01/2012 - "The cytotoxic activity and anticancer mechanisms of alterporriol L towards breast cancer cells lines were detected using MTT assay, immunofluorescence, and flow cytometry. " 01/01/2012 - "The cytotoxicity and anticancer mechanisms of alterporriol L, a marine bianthraquinone, against MCF-7 human breast cancer cells." 01/01/2012 - "Furthermore, the reactive oxygen species, mitochondrial membrane potential, and cytosolic free calcium level were changed after treatment with alterporriol L, suggesting that alterporriol L played vital roles in breast cancer cells through destroying the mitochondrial. "

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	Calcium

Related Therapies and Procedures

1.	Aftercare (After-Treatment)