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UBP 310

a GluR5 antagonist; structure in first source

Also Known As:

UBP-310; UBP310

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Alanine: 4133
    - UBP 310: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Thymine: 735
        UBP 310: 3

Experts

1.	Huang, Ya-Lin: 1 article (01/2019)
2.	Kou, Zeng-Wei: 1 article (01/2019)
3.	Lei, Yu: 1 article (01/2019)
4.	Lv, Ling-Ling: 1 article (01/2019)
5.	Mo, Jia-Lin: 1 article (01/2019)
6.	Qiu, Mei-Hong: 1 article (01/2019)
7.	Sun, Feng-Yan: 1 article (01/2019)
8.	Tao, Feng: 1 article (01/2019)
9.	Wu, Kun-Wei: 1 article (01/2019)
10.	Grosenbaugh, Denise K: 1 article (01/2018)

Related Diseases

1.	Hypoxia (Hypoxemia) 01/01/2018 - "This increase was absent in slices from GluK2-/- mice and in slices treated with UBP310, suggesting that KARs regulate, at least in part, excitatory synaptic neurotransmission following in vivo hypoxia in neonatal mice. " 01/01/2018 - "Following the hypoxic insult, we observed an increase in excitatory neurotransmission in hippocampal CA3 pyramidal cells, which was blocked by treatment with UBP310 prior to hypoxia. " 01/01/2019 - "We found that VEGF quickly inhibited the glutamate/hypoxia-induced calcium influx, which was blocked by an AMPA receptor antagonist CNQX, but not D-AP5 or UBP310, NMDA and kainate receptor antagonist, respectively. "
2.	Pruritus (Itching) 10/15/2023 - "On the other hand, UBP310 or UBP302 and the siRNAs of KA receptor subunits 1-3 significantly inhibited the induction of scratching events in mice treated with histamine, while no significant change was observed in the induction of spontaneous scratching events in mice with chronic pruritus. " 10/15/2023 - "Therefore, the roles of KA receptors in histamine-dependent and -independent itch were investigated using CNQX, an AMPA/KA receptors antagonist, UBP310 and UBP302, antagonists of KA receptors, and small interfering (si)RNAs against KA receptor subunits in mice with acute and chronic pruritus. "

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