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sebacoyl dinalbuphine ester

a nalbuphine prodrug; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kuo, Ping-Chung: 1 article (05/2021)
2.	Lin, Shang-Wen: 1 article (05/2021)
3.	Shyong, Yan-Jye: 1 article (05/2021)
4.	Tsai, Jui-Chen: 1 article (05/2021)

Related Diseases

1.	Chronic Pain 01/01/2023 - "Efficacy and Safety of Parenteral Injection of an Extended Release κ-receptor Opioid Sebacoyl Dinalbuphine Ester for Acute and Chronic Pain After Laparoscopic Bariatric Surgery: a Randomized, Placebo-Controlled, Double-Blind Trial."
2.	Pain (Aches) 01/01/2023 - "This double-blind clinical trial tested an extended-release κ-receptor agonist, sebacoyl dinalbuphine ester (SDE, Naldebain®) for management of surgical pain after laparoscopic bariatric surgery. " 05/01/2021 - "Sebacoyl dinalbuphine ester (SDE) is a nalbuphine (NA) prodrug capable of biotransformation in vivo and prolong the duration of NA, maximize its effect in pain and pruritus management. "
3.	Pruritus (Itching) 05/01/2021 - "Topical application of sebacoyl dinalbuphine ester-loaded nanostructured lipid carriers alleviate pruritus in scratching mouse model." 05/01/2021 - "Sebacoyl dinalbuphine ester (SDE) is a nalbuphine (NA) prodrug capable of biotransformation in vivo and prolong the duration of NA, maximize its effect in pain and pruritus management. "

Related Drugs and Biologics

1.	Opioid Receptors (Opioid Receptor)
2.	Prodrugs
3.	Nalbuphine (Nubain)
4.	Lipids

Related Therapies and Procedures

1.	Bariatric Surgery