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2- cyano- 3- hydroxy- N- (4- (trifluoromethyl)phenyl)- 2- hepten- 6- ynamide

structure in first source; a derivative of A77 1726, the active metabolite of the antirheumatic drug leflunomide, where the isoxazole ring has opened to become a nitrile and an alkyne
Also Known As:
2-cyano-3-hydroxy-N-(4--(trifluoromethyl)phenyl)-2-hepten-6-ynoic acid; FK 778; FK-778; FK778; HMR 1715; HMR-1715; MNA 715; MNA-715; MNA-X 920715; X 920715; X-920715; malononitrilamide 715; malononitrilamide-715
Networked: 22 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kloppenburg, Geoffrey: 2 articles (03/2009 - 01/2009)
2. Stassen, Frank: 2 articles (03/2009 - 01/2009)
3. de Graaf, Rick: 2 articles (03/2009 - 01/2009)
4. Schrepfer, Sonja: 2 articles (01/2007 - 01/2007)
5. Schäfer, Hansjörg: 2 articles (01/2007 - 01/2007)
6. Deuse, Tobias: 2 articles (01/2007 - 01/2007)
7. Robbins, Robert C: 2 articles (01/2007 - 01/2007)
8. Haddad, Munif: 2 articles (01/2007 - 01/2007)
9. Pelletier, Marc P: 2 articles (01/2007 - 01/2007)
10. Reichenspurner, Hermann: 2 articles (01/2007 - 01/2007)

Related Diseases

1. Infection
2. Fibrosis (Cirrhosis)
3. Neointima
4. Hyperplasia
5. Proteinuria

Related Drugs and Biologics

1. Tacrolimus (Prograf)
2. leflunomide (Arava)
3. X 910279
4. Sirolimus (Rapamycin)
5. Cyclosporine (Ciclosporin)
6. Immunosuppressive Agents (Immunosuppressants)
7. Creatinine
8. Proteins (Proteins, Gene)
9. Viral DNA
10. glucuronyl glucosamine glycan sulfate (Vessel)

Related Therapies and Procedures

1. Oral Administration
2. Heart Transplantation (Grafting, Heart)
3. Transplants (Transplant)
4. Homologous Transplantation (Allograft)
5. Angioplasty (Angioplasty, Transluminal)