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Ralitoline
Also Known As:
acetamide, N-(2-chloro-6-methylphenyl)-2-(3-methyl-4-oxo-2- thiazolidinylidene)-, (Z)-
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazoles: 392
Ralitoline: 3
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Thiazoles: 392
Ralitoline: 3
Related Diseases
1.
Seizures (Absence Seizure)
10/01/1992 - "
In conclusion, the findings confirm the potent anticonvulsant effects of ralitoline, especially against generalized tonic-clonic and complex partial seizures.
"
10/01/1992 - "
In the strychnine seizure test (mice), ralitoline (5 and 10 mg/kg) prolonged the latency of tonic seizures as well as the survival time.
"
06/01/1987 - "
We distinguished at least three types of drugs: Phenytoin and ralitoline selectively prevented tonic-clonic seizures; the other drugs tested were active against all seizure types.
"
04/01/1991 - "
Ralitoline and CI-953 are anticonvulsant compounds active in both maximal electroshock and kindling models of seizures with rodents.
"
2.
Epilepsy (Aura)
10/01/1992 - "
Ralitoline, a thiazolidinone derivative chemically distinct from known antiepileptic drugs, possesses remarkable anticonvulsant properties as demonstrated in various animal models of epilepsy.
"
Related Drugs and Biologics
1.
Anticonvulsants (Antiepileptic Drugs)
2.
Strychnine
3.
Phenytoin (Dilantin)
4.
CI 953