coproporphyrin I

RN given refers to cpd with specified locants; see also record for coproporphyrin III; zinc coproporphyrin I is fluorescent and a characteristic component of meconium
Also Known As:
Pd-coproporphyrin I; zinc coproporphyrin I
Networked: 17 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Suzuki, K: 1 article (01/2012)
2. Tamura, N: 1 article (01/2012)
3. Itoh, H: 1 article (01/2012)
4. Suzuki, N: 1 article (01/2012)
5. Kanayama, N: 1 article (01/2012)
6. Kato, M: 1 article (01/2012)
7. Sugihara, K: 1 article (01/2012)
8. Uchida, T: 1 article (01/2012)
9. Furuta, N: 1 article (01/2012)
10. Sasaki, T: 1 article (01/2012)

Related Diseases

1. Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency)
2. Porphyrias
12/01/1995 - "Our results clearly demonstrate the potential of faecal coproporphyrin I-IV isomer ratios for the diagnosis and differential diagnosis of hereditary porphyrias."
06/01/1976 - "Administration of griseofulvin, in the dose which had been shown to precipitate attacks of acute porphyria in susceptible subjects, to carriers and patients with DJS did not elicit clinical signs suggestive of porphyria, and urinary total coproporphyrin concentration and the percentage of coproporphyrin I remained unchanged. "
09/01/1992 - "The proband's levels of total porphyrins, urinary uroporphyrin I, and erythrocyte coproporphyrin I were elevated, but not as dramatically as in other patients with this porphyria. "
04/01/1992 - "The day-to-day variation of assays of standards was lower with the robot than with the manual operation: 8% (CV) for coproporphyrin I and 11% for protoporphyrin IX. We repeatedly analyzed a specimen from a healthy volunteer and determined that the specimen contained (in nmol/g dry wt) 7.1 (SD 0.7) for coproporphyrin I, 3.0 (SD 0.4) for coproporphyrin III, and 44.4 (SD 4.3) for protoporphyrin IX. Upper reference limits as measured in 20 healthy volunteers were 20 nmol/g dry wt for coproporphyrin I, 12 nmol/g for coproporphyrin III, and 80 nmol/g for protoporphyrin IX. We also present characteristic chromatograms for samples from various different porphyrias that exhibit abnormal fecal porphyrin excretion. "
10/01/1993 - "Results showed a significant decrease (p < 0.001) of the proportion of coproporphyrin I in acute hepatic porphyria (acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, porphobilinogen synthase deficiency porphyria) as compared with chronic hepatic porphyria (porphyria cutanea tarda, chronic hepatic porphyria type B and C) (13.2 +/- 5.3%, mean +/- S.D., vs. 31.4 +/- 11.5%). "
3. Hereditary Coproporphyria (Coproporphyrinogen Oxidase Deficiency)
4. Acute Intermittent Porphyria (Porphyria, Acute)
5. Erythropoietic Protoporphyria

Related Drugs and Biologics

1. Porphyrins
2. uroporphyrin I
3. coproporphyrin III
4. Griseofulvin (Grifulvin V)
5. Coproporphyrinogen Oxidase (Coproporphyrinogen III Oxidases)
6. Porphobilinogen Synthase (delta-Aminolevulinate Dehydratase)
7. protoporphyrin IX