|1.||Barone, Eugenio: 6 articles (02/2014 - 01/2011)|
|2.||Di Domenico, Fabio: 6 articles (02/2014 - 01/2011)|
|3.||Mancuso, Cesare: 5 articles (02/2014 - 01/2011)|
|4.||Butterfield, D Allan: 5 articles (02/2014 - 01/2011)|
|5.||Perluigi, Marzia: 4 articles (07/2013 - 01/2011)|
|6.||Sultana, Rukhsana: 3 articles (01/2012 - 01/2011)|
|7.||Maines, Mahin D: 2 articles (01/2015 - 09/2010)|
|8.||Miralem, Tihomir: 2 articles (01/2015 - 09/2010)|
|9.||Gibbs, Peter E M: 2 articles (01/2015 - 09/2010)|
|10.||Kim, Sung Su: 2 articles (11/2013 - 11/2013)|
11/01/2007 - "Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway."
02/01/2008 - "In conclusion, biliverdin reductase mediates hypoxia-induced EMT through a PI3K/Akt-dependent pathway."
02/01/2008 - "We investigated this potential role of biliverdin reductase in hypoxia-induced renal tubular EMT. "
11/01/2013 - "Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma."
08/01/2013 - "Biliverdin reductase/bilirubin mediates the anti-apoptotic effect of hypoxia in pulmonary arterial smooth muscle cells through ERK1/2 pathway."
|2.||Alzheimer Disease (Alzheimer's Disease)
01/01/2011 - "Oxidative and nitrosative modifications of biliverdin reductase-A in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment."
01/01/2012 - "Several studies showed increased oxidative and nitrosative stress in plasma from patients with Alzheimer's disease (AD), however, little and controversial knowledge has emerged about the antioxidant functionality of the heme oxygenase-1/biliverdin reductase-A (HO-1/BVR-A) system in blood. "
02/01/2014 - "The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: it's time for reconciliation."
01/01/2012 - "Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease."
04/01/2011 - "Consequently, not just the increased levels of biliverdin reductase-A, but also its changed activity and phosphorylation state, should be taken into account when considering potential biomarkers for Alzheimer disease and mild cognitive impairment."
|3.||Movement Disorders (Movement Disorder)
03/01/2012 - "Concentrations in excess of 300 μM corresponded to dose dependent loss of cell viability which was associated with enhanced production of H(2)O(2) concomitant to elevation of gene expression for diverse antioxidant enzymes; biliverdin reductase, arsenite inducible RNA associated protein, dithiolethione-inducible gene-1 (DIG-1) and thioredoxin reductase 1. Moreover, Mn initiated significant reduction of gene expression of mitochondrial glutaryl-coenzyme A dehydrogenase (GCDH), an enzyme involved with glutaric acidemia, oxidative stress, lipid peroxidation and striatal degeneration observed in association with severe dystonic-dyskinetic movement disorder. "
01/01/2015 - "Biliverdin reductase: a target for cancer therapy?"
10/01/1999 - "tissue sections were used for immunostaining of biliverdin reductase, pooled isolated tumors and surrounding tissue that did not contain visible tumor were used for Northern blot analysis of mRNA and Western blot analysis of protein. "
01/01/2007 - "Among a number of signals that were detected as significantly different in the protein profiling analysis, we identified for the first time ferritin light subunit (FLS) and adenylate kinase 3 alpha-like 1 (AK3), showing decreased expressions in hepatic tumor, as well as biliverdin reductase B (BVRB) that was upregulated in HCC. "
11/15/2011 - "We hypothesized that biliverdin reductase (BVR) by binding biliverdin (BV) quells the cellular response to endotoxin-induced inflammation through phosphorylation of endothelial nitric oxide synthase (eNOS). "
01/01/2014 - "The HO system and related products such as carbon monoxide, bilirubin, biliverdin, biliverdin reductase and ferritin have been shown to abate inflammation, oxidative stress, and apoptosis and reduce hyperglycemia. "
07/01/2004 - "Inducible heme oxygenase-1 and downstream proteins biliverdin reductase and p21, a cyclin-dependent kinase, were up-regulated, potentially contributing to phenotypic heterogeneity and absence of atherosclerosis in patients with sickle cell disease despite endothelial dysfunction and vascular inflammation. "
|4.||Thioredoxin Reductase 1
|6.||RNA (Ribonucleic Acid)
|10.||Heme Oxygenase (Decyclizing) (Heme Oxygenase)