aconitate decarboxylase

Networked: 13 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 09/17/2023 - "Here, we find that αPD-1-resistant cancer cells produce abundant itaconate (ITA) due to enhanced levels of aconitate decarboxylase (Acod1). " 10/03/2023 - "Here, using single-cell RNA sequencing to compare TINs and circulating neutrophils in murine mammary tumor models, we identified aconitate decarboxylase 1 (Acod1) as the most upregulated metabolic enzyme in mouse TINs and validated high Acod1 expression in human TINs. "
2.	Infections 01/01/2020 - "Aconitate decarboxylase 1 (ACOD1; also known as IRG1) is emerging as a regulator of immunometabolism in inflammation and infection. " 01/01/2023 - "In addition, the metabolic phenotype of the prefrontal cortex post infection was characterized by the enhancement of glycolysis and fatty acid oxidation, the blockage of the Krebs cycle, and the disorder of aconitate decarboxylase 1 (ACOD1)-itaconate axis. "
3.	Ulcerative Colitis 01/20/2023 - "Cepharanthine Alleviates DSS-Induced Ulcerative Colitis via Regulating Aconitate Decarboxylase 1 Expression and Macrophage Infiltration." 04/15/2022 - "However, the association between the Acod1 (Aconitate decarboxylase 1)-itaconate axis and ulcerative colitis has rarely been studied. "
4.	Sepsis (Septicemia) 01/01/2022 - "Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis."
5.	Reperfusion Injury 01/01/2022 - "Aconitate decarboxylase 1 suppresses cerebral ischemia-reperfusion injury in mice."

1.	itaconic acid
2.	Enzymes
3.	Long Noncoding RNA
4.	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)
5.	RNA (Ribonucleic Acid)
6.	Phosphotransferases (Kinase)
7.	Leucine (L-Leucine)
8.	Glucose (Dextrose)
9.	Fatty Acids (Saturated Fatty Acids)
10.	Dextrans (Dextran)