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5-vinyl-2'-deoxyuridine
structure
Also Known As:
2'-deoxy-5-vinyluridine; 2'-deoxy-5-ethenyluridine
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidine Nucleosides: 50
Uridine: 1186
Deoxyuridine: 331
5-vinyl-2'-deoxyuridine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Pyrimidine Nucleosides: 50
Uridine: 1186
Deoxyuridine: 331
5-vinyl-2'-deoxyuridine: 2
Deoxyribonucleosides: 34
Deoxyuridine: 331
5-vinyl-2'-deoxyuridine: 2
Related Diseases
1.
Neoplasms (Cancer)
10/01/2023 - "
For cancer treatment, nucleoside analogues (NA) such as 5-vinyl-2'-deoxyuridine (VdU) can be metabolically incorporated into cancer cell DNA and subsequently "clicked" to form a toxic product.
"
10/01/2023 - "
DNA templated Click Chemistry via 5-vinyl-2'-deoxyuridine and an acridine-tetrazine conjugate induces DNA damage and apoptosis in cancer cells.
"
01/01/1980 - "
The chemical syntheses of some 5-substituted uracil deorivatives, in particular 5-vinyl-2'-deoxyuridine, 5-ethynyl-2'-deoxyuridine and 4-(2-bromovinyl)-2'-deoxy-uridine are reviewed and their potential as radiation sensitizing agents, anti-cancer agents and antiviral agents is discussed.
"
Related Drugs and Biologics
1.
Uracil
2.
Radiation-Sensitizing Agents
3.
Nucleosides
4.
DNA (Deoxyribonucleic Acid)
5.
Antiviral Agents (Antivirals)
6.
Acridines
7.
5-ethynyl-2'-deoxyuridine