6-(4-hydroxyphenylhydrazino)uracil

antimicrobial agent which selectively blocks replication of DNA synthesis in Bacillus subtilis by inhibiting DNA polymerase III

Also Known As:

6-(p-hydroxyphenylazo)uracil; 6-(p-hydroxyphenylhydrazino)uracil; H2-HPUra; 6-(2-(4-hydroxyphenyl)hydrazino)-2,4(1H,3H)- pyrimidinedione

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Clostridium Infections 01/01/2019 - "This review therefore examines the evolution of DNA pol IIIC inhibitors from the discovery of 6-(p-hydroxyphenylazo)uracil (HPUra) in the 1960s to the development of current first-in-class N7-substituted guanine drug candidate ACX-362E, now under clinical development for the treatment of Clostridioides difficile infection."