|1.||Wang, Wei: 2 articles (07/2013 - 01/2013)|
|2.||Luo, Meng: 2 articles (07/2013 - 01/2013)|
|3.||Sun, Yao: 2 articles (07/2013 - 01/2013)|
|4.||Fu, Yujie: 2 articles (07/2013 - 01/2013)|
|5.||Zu, Yuangang: 2 articles (07/2013 - 01/2013)|
|6.||Hua, Xin: 1 article (10/2015)|
|7.||Wan, Daqian: 1 article (10/2015)|
|8.||Jiang, Chaoyin: 1 article (10/2015)|
|9.||Chai, Yimin: 1 article (10/2015)|
|10.||Wang, Ting: 1 article (10/2015)|
|1.||Ovarian Neoplasms (Ovarian Cancer)
07/05/2013 - "In this study, we analyzed the underlying mechanisms of aspidin BB on human ovarian cancer cell line, HO-8910. "
07/05/2013 - "Taken together, these findings support the conclusion that aspidin BB exhibits cytotoxicity towards human ovarian cancer HO-8910 cells through induction of apoptosis via mitochondrial pathway and arresting cell cycle progression in S phase."
|2.||Hepatocellular Carcinoma (Hepatoma)
10/01/2015 - "In addition, aspidin PB inhibited tumor growth significantly in U2OS xenografts. "
08/01/2000 - "Amongst the isolates, aspidin PB (8), dryofragin (9), and 1-5 exhibited potent ichthyotoxic activity against medaka with a median tolerance limit (TLm after 24 h) of 1.2-4.3 microg/ml. These compounds which are toxic to fish also had a potent inhibitory effect on the activation of Epstein-Barr virus early-antigen (EBV-EA) induced by tetradecanoyl phorbol 13-acetate, which is an in vitro short-term assay for anti-tumor promoting agents. "
08/02/1996 - "The two dimeric compounds aspidin and desaspidin, which were found to be the most active among the tested phlorophenones, were also examined in vivo on two stage mouse skin carcinogenesis, and found to show significant inhibitory effect on 7,12-dimethylbenz[alpha]anthracene (DMBA)-TPA tumor promotion."
04/01/2014 - "Phytochemicals in the class of flavonoids (apigenin, quercetin, isoliquiritigenin, and 2'-hydroxyflavanone), isoflavonoids (formononetin and genistein), catechins (epigallocatechin gallate and epicatechin gallate), stilbenoids (resveratrol and pinosylvin), phenolics (6-gingerol), phloroglucinols (rottlerin and aspidin PB), terpenoids (18 α-glycyrrhetinic acid, platycodin D, pseudolaric acid B, and xanthorrhizol), alkaloids (berberine, capsaicin, and indole-3-carbinol), lignans (isochaihulactone), anthraquinones (damnacanthal), and allyl sulfides (diallyl disulfide) elicited NAG-1 overexpression in various cancer cells. "
|4.||Osteosarcoma (Osteogenic Sarcoma)
10/01/2015 - "Above all, we conclude that aspidin PB represents a valuable natural source and may potentially be applicable in osteosarcoma therapy. "
10/01/2015 - "We reported that aspidin PB induced cell cycle arrest and apoptosis through the p53/p21 and mitochondria-dependent pathways in human osteosarcoma cells. "
10/01/2015 - "Cell cycle arrest and apoptosis induced by aspidin PB through the p53/p21 and mitochondria-dependent pathways in human osteosarcoma cells."
08/05/2015 - "Our findings imply that aspidin PB has a therapeutic potential to intervene and prevent keloids and other fibrotic diseases. "
08/05/2015 - "The effect of aspidin PB on cell viability in human keloid fibroblasts was measured by MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide). "
08/05/2015 - "Aspidin PB, a novel natural anti-fibrotic compound, inhibited fibrogenesis in TGF-β1-stimulated keloid fibroblasts via PI-3K/Akt and Smad signaling pathways."
|8.||Glycyrrhetinic Acid (Po 12)
|1.||Heterologous Transplantation (Xenotransplantation)