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compound 30666

Also Known As:

7-(((4-methyl-2-pyridinyl)amino)(2-pyridinyl)methyl)-8-quinolinol

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - compound 30666: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Hydroxyquinolines: 9
        compound 30666: 2

Experts

1.	Dzikiewicz-Krawczyk, Agnieszka: 1 article (11/2021)
2.	Kasprzyk, Marta Elżbieta: 1 article (11/2021)
3.	Kazimierska, Marta: 1 article (11/2021)
4.	Podralska, Marta: 1 article (11/2021)
5.	Sura, Weronika: 1 article (11/2021)
6.	Łosiewski, Wojciech: 1 article (11/2021)
7.	Dolloff, Nathan G: 1 article (01/2019)

Related Diseases

1.	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/05/2021 - "Here, we aimed to test the effect of compound 30666 in Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) and shed light on its mechanism of action. "
2.	B-Cell Lymphoma (Lymphoma, B Cell) 11/05/2021 - "7-[[(4-methyl-2-pyridinyl)amino](2-pyridinyl)methyl]-8-quinolinol (compound 30666) inhibits enhancer activity and reduces B-cell lymphoma growth - A question of specificity."
3.	Plasmacytoma 01/01/2019 - "Compound 30666 exhibited suitable pharmacological properties, including metabolic stability in liver microsomes and oral bioavailability in mice, and demonstrated preclinical anti-MM activity in a plasmacytoma mouse model. "
4.	Multiple Myeloma 11/05/2021 - "Recently, a small molecule - 7-[[(4-methyl-2-pyridinyl)amino](2-pyridinyl)methyl]-8-quinolinol (compound 30666) was identified to decrease activity of the Eμ enhancer and reduce the expression of translocated oncogenes in multiple myeloma and some NHL cell lines (Dolloff, 2019). "
5.	Burkitt Lymphoma (Burkitt's Lymphoma) 11/05/2021 - "Here, we aimed to test the effect of compound 30666 in Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) and shed light on its mechanism of action. "

Related Drugs and Biologics

1.	Oxyquinoline (8 Hydroxyquinoline)