Brucella unlipidated outer membrane protein 19

unlipidated outer membrane protein 19 isolated from multiple Brucella species (spp.) investigated for use as vaccine adjuvant as well as a vaccine against brucellosis

Also Known As:

unlipidated outer membrane protein 19, Brucella; U-Omp 19; U-Omp19; unlipidated outer membrane protein 19, Brucella species; unlipidated outer membrane protein 19, Brucella spp.

Networked: 9 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Cassataro, Juliana: 6 articles (01/2020 - 01/2009)
2.	Coria, Lorena M: 5 articles (01/2020 - 01/2009)
3.	Pasquevich, Karina A: 5 articles (01/2020 - 01/2009)
4.	Ibañez, Andrés E: 3 articles (01/2017 - 01/2016)
5.	Giambartolomei, Guillermo H: 3 articles (01/2016 - 01/2009)
6.	Barrionuevo, Paula: 3 articles (01/2016 - 01/2009)
7.	Bruno, Laura A: 2 articles (01/2020 - 01/2017)
8.	Briones, Gabriel: 2 articles (01/2017 - 12/2015)
9.	Carabajal, Marianela V: 2 articles (01/2017 - 01/2016)
10.	Bruno, Laura: 2 articles (01/2016 - 12/2015)

Related Diseases

1.	Parasitemia 01/20/2016 - "Finally, subcutaneous co-administration of U-Omp19 with Trypanosoma cruzi Ags confers protection against virulent parasite challenge, reducing parasitemia and weight loss while increasing mice survival. "
2.	Weight Loss (Weight Reduction) 01/20/2016 - "Finally, subcutaneous co-administration of U-Omp19 with Trypanosoma cruzi Ags confers protection against virulent parasite challenge, reducing parasitemia and weight loss while increasing mice survival. "
3.	Salmonella Infections (Salmonellosis) 01/01/2017 - "These findings prove the efficacy of this novel adjuvant in the Salmonella infection model and support the potential of U-Omp19 as a suitable adjuvant in oral vaccine formulations against mucosal pathogens requiring T helper (Th)1-Th17 protective immune responses." 01/01/2017 - "U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice."
4.	Communicable Diseases (Infectious Diseases) 01/20/2016 - "These results indicate that the bacterial protein U-Omp19 when delivered subcutaneously could be a suitable component of vaccine formulations against infectious diseases requiring Th1 immune responses. " 12/28/2015 - "We report here that a bacterial protease inhibitor from Brucella spp. called U-Omp19 behaves as an ideal constituent for a vaccine formulation against infectious diseases. " 01/01/2022 - "This information may lead to future rationale vaccine designs using U-Omp19 as an adjuvant to deliver other proteins or peptides in oral formulations against infectious diseases, as well as to design strategies to incorporate modifications in its structure that may improve its adjuvanticity."
5.	Brucellosis (Malta Fever) 04/01/2016 - "Recombinant lipoproteins L-OMP19 and U-OMP19 expressed in cells have a good antigenicity, which could be used as experimental materials for the research on the relationship between host cells and lipoproteins in Brucella infection." 01/01/2009 - "Overall these results indicate that U-Omp16 or U-Omp19 would be a useful candidate for a subunit vaccine against human and animal brucellosis."

Related Drugs and Biologics

1.	Vaccines
2.	Proteins (Proteins, Gene)
3.	Subunit Vaccines
4.	Protease Inhibitors (Protease Inhibitor)
5.	Peptides (Polypeptides)
6.	Lipoproteins (Lipoprotein)
7.	Bacterial Proteins (Bacterial Protein)