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OAMDP compound

induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells

Also Known As:

4beta-(1,3,4-oxadiazole-2-amino-5-methyl)-4-deoxypodophyllotoxin; OAMDP

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Lin: 1 article (02/2018)
2.	Hu, Kun: 1 article (02/2018)
3.	Li, Lixia: 1 article (02/2018)
4.	Li, Zhongyu: 1 article (02/2018)
5.	Liu, Yu: 1 article (02/2018)
6.	Ren, Jie: 1 article (02/2018)
7.	Wu, Chao: 1 article (02/2018)
8.	Zhao, Yuexin: 1 article (02/2018)

Related Diseases

1.	Neoplasms (Cancer) 02/01/2018 - "To sum up, our results suggested that OAMDP, with the ability to induce autophagy, causing cell cycle arrest and apoptosis, has potential to become a novel anti-tumor agent." 02/01/2018 - "4β-(1,3,4-oxadiazole-2-amino-5-methyl)-4-deoxypodophyllotoxin (OAMDP), a novel podophyllotoxin derivative, has demonstrated potent anti-tumor activity with significant cytotoxic effect. "
2.	Hepatocellular Carcinoma (Hepatoma) 02/01/2018 - "Here, we report the anti-proliferative effect of OAMDP, for which OAMDP could suppress the proliferation of HepG2 cells (human hepatoma cell line) in a dose- and time-dependent manner. " 02/01/2018 - "OAMDP, a novel podophyllotoxin derivative, induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells."

Related Drugs and Biologics

1.	Podophyllotoxin (Condylox)