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Podophyllotoxin (Condylox)

A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
Also Known As:
Condylox; Wartec; Epipodophyllotoxin; CPH86; Condyline; Podocon-25; Podofilm; Podofilox; Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer; Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer; Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer; Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer; Warticon; Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-
Networked: 562 relevant articles (48 outcomes, 71 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Kamal, Ahmed: 11 articles (01/2019 - 11/2003)
2. Zhang, Lei: 9 articles (01/2020 - 01/2016)
3. Wang, Jing: 9 articles (01/2019 - 01/2016)
4. Chen, Hong: 7 articles (11/2019 - 02/2010)
5. Chen, Yongzheng: 7 articles (01/2019 - 01/2016)
6. Zeng, Kang: 5 articles (07/2022 - 05/2007)
7. Zhang, Shubiao: 4 articles (07/2022 - 01/2022)
8. Zhao, Yinan: 4 articles (07/2022 - 01/2022)
9. Gupta, Manju Lata: 4 articles (07/2020 - 01/2017)
10. Li, Shyh-Dar: 4 articles (08/2017 - 06/2015)

Related Diseases

1. Warts (Wart)
2. Neoplasms (Cancer)
3. Condylomata Acuminata (Genital Wart)
4. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Solutions
2. Etoposide (VP 16)
3. Imiquimod (Aldara)
4. Podophyllin
5. Teniposide (VM 26)
6. Salicylic Acid (2 Hydroxybenzoic Acid)
7. Cantharidin (Cantharides)
8. Anthracyclines
9. Vincristine (Oncovin)
10. Vinblastine (Vinblastine Sulfate)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Cryotherapy (Therapy, Cold)
4. Laser Therapy (Surgery, Laser)
5. Remission Induction