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isogambogenic acid

has antineoplastic activity; structure in first source

Also Known As:

iso-GNA

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Xanthenes: 65
      - Xanthones: 211
        isogambogenic acid: 4

Experts

1.	Chen, Lijuan: 3 articles (04/2020 - 10/2013)
2.	Fan, Yi: 3 articles (04/2020 - 10/2013)
3.	He, Shichao: 3 articles (04/2020 - 10/2013)
4.	Peng, Aihua: 3 articles (04/2020 - 10/2013)
5.	Cheng, Xia: 2 articles (04/2020 - 01/2015)
6.	Li, Chunyan: 2 articles (04/2020 - 01/2015)
7.	Li, Luyuan: 2 articles (04/2020 - 01/2015)
8.	Li, Shucai: 2 articles (04/2020 - 01/2015)
9.	Li, Weimin: 2 articles (04/2020 - 01/2015)
10.	Pei, Heying: 2 articles (04/2020 - 01/2015)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2013 - "A standard methyl thiazolyl tetrazolium assay showed that iso-GNA was more effective in inhibiting the proliferation of human umbilical vascular endothelial cells than A549 cancer cells. " 10/01/2013 - "Together, these data suggest that iso-GNA inhibits angiogenesis and may be a viable drug candidate in anti-angiogenesis and anti-cancer therapies. "
2.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/20/2020 - "Author Correction: Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells." 01/09/2015 - "Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells."
3.	Glioma (Gliomas) 01/01/2017 - "Finally, isogambogenic acid inhibited the growth of U87 glioma in vivo. " 01/01/2017 - "Inhibition of autophagy attenuated apoptosis in isogambogenic acid-treated glioma cells. " 01/01/2017 - "Moreover, we observed the activation of AMPK-mTOR signalling in isogambogenic acid-treated glioma cells. " 01/01/2017 - "U87-derived xenografts were established for the examination of the effect of isogambogenic acid on glioma growth in vivo. " 01/01/2017 - "Isogambogenic Acid Inhibits the Growth of Glioma Through Activation of the AMPK-mTOR Pathway."

Related Therapies and Procedures

1.	Therapeutics