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ciliobrevin A

has antineoplastic activity

Also Known As:

HPI-4 compound; hedgehog pathway inhibitor-4

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - Quinazolinones: 124
        ciliobrevin A: 2

Experts

1.	Berra, Carolina M: 1 article (01/2016)
2.	Bosch, Rosemary V: 1 article (01/2016)
3.	Branco, Vania G: 1 article (01/2016)
4.	Chudzinski-Tavassi, Ana Marisa: 1 article (01/2016)
5.	Demasi, Marilene: 1 article (01/2016)
6.	Iqbal, Asif: 1 article (01/2016)
7.	Morais, Kátia L P: 1 article (01/2016)
8.	Pacheco, Mario T F: 1 article (01/2016)
9.	Sciani, Juliana M: 1 article (01/2016)
10.	Cheng, Weiting: 1 article (10/2014)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2014 - "Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis." 01/15/2016 - "Moreover, dynein inhibitor, ciliobrevin A, decreased Amblyomin-X uptake by tumor cells. " 01/15/2016 - "Furthermore, incubation of tumor cells with Amblyomin-X inhibited trypsin-like activity of the proteasome, which was restored upon pretreatment with ciliobrevin A. "
2.	Chondrosarcoma 10/01/2014 - "Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis."

Related Drugs and Biologics

1.	Proteasome Endopeptidase Complex (Proteasome)
2.	Trypsin
3.	Dyneins (Dynein)