Hormonal changes in the postpartum and implications for postpartum depression.

Abstract

The months following childbirth are a time of heightened vulnerability to depressive mood changes. Because of the abrupt and dramatic changes occurring in hormone levels after delivery, many studies have examined the role of hormonal factors in postpartum depression. The authors review the literature on potential hormonal etiologies in postpartum depression, in particular for progesterone, estrogen, prolactin, cortisol, oxytocin, thyroid, and vasopressin. While evidence for an etiologic role is lacking for most hormones, changes in certain hormonal axes may contribute to depressive mood changes in some women following childbirth.

• Authors: V Hendrick, L L Altshuler, R Suri
• Journal: Psychosomatics (Psychosomatics) 1998 Mar-Apr Vol. 39 Issue 2 Pg. 93-101 ISSN: 0033-3182 [Print] England
• PMID: 9584534 (Publication Type: Journal Article, Review)

Chemical References

• Estrogens
• Pituitary Hormones
• Thyroid Hormones
• Progesterone
• Hydrocortisone

Topics

• Depression, Postpartum (blood, psychology)
• Estrogens (blood)
• Female
• Humans
• Hydrocortisone (blood)
• Pituitary Hormones (blood)
• Pregnancy
• Progesterone (analysis, blood)
• Thyroid Hormones (blood)