Abstract | PURPOSE: MATERIALS AND METHODS: A total of 337 women with at least a 1-year history, physical findings and urodynamic abnormalities consistent with stress urinary incontinence, who required pads or protective clothing, and who had no or only grade 1 cystocele were enrolled in this prospective cohort study. A third party documented adverse effects at each followup. RESULTS: De novo urinary urgency with incontinence was the most frequent and serious complication, occurring in 12.6% of patients, and in many the symptoms were irreversible. Hematuria (5% of patients) and urinary retention (1.9%) were short-lived and resolved spontaneously. Delayed reaction at the skin test site occurred in 0.9% of the patients (3) and was associated with arthralgias in 2. CONCLUSIONS: Contrary to previous reports that periurethral collagen injection is complication-free, we found an overall incidence of 20% risk of complications in any given individual.
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Authors | L Stothers, S L Goldenberg, E F Leone |
Journal | The Journal of urology
(J Urol)
Vol. 159
Issue 3
Pg. 806-7
(Mar 1998)
ISSN: 0022-5347 [Print] United States |
PMID | 9474154
(Publication Type: Journal Article)
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Chemical References |
- Biocompatible Materials
- Cross-Linking Reagents
- glutaraldehyde-cross-linked collagen
- Collagen
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Topics |
- Biocompatible Materials
(administration & dosage, adverse effects)
- Collagen
(administration & dosage, adverse effects)
- Cross-Linking Reagents
(administration & dosage, adverse effects)
- Female
- Humans
- Injections, Intralesional
- Prospective Studies
- Urinary Incontinence, Stress
(therapy)
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