Hematuria

1.	Proteinuria
2.	Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
3.	IGA Glomerulonephritis (IGA Nephropathy)
4.	Flank Pain
5.	Urinary Bladder Neoplasms (Bladder Cancer)

Experts

1.	Gill, Harcharan: 1 article (10/2008)
2.	Tu, William H: 1 article (10/2008)
3.	Chao, Debbie: 1 article (10/2008)
4.	Buzing, C: 1 article (06/2008)
5.	Meijer, J: 1 article (06/2008)
6.	Lohkamp, B: 1 article (06/2008)
7.	Dobritzsch, D: 1 article (06/2008)
8.	Ruitenbeek, W: 1 article (06/2008)
9.	Roelofsen, J: 1 article (06/2008)
10.	van Kuilenburg, A B P: 1 article (06/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hematuria:

1.	Finasteride (Propecia)FDA LinkGeneric 01/01/2001 - "CONCLUSION: Finasteride has proved to be a safe, well tolerable and effective medication in reducing or preventing recurrent hematuria related to BPH." 11/01/1995 - "CONCLUSIONS: Finasteride is effective in treating hematuria associated with BPH. " 06/01/2002 - "RESULTS: Hematuria grade improved after finasteride in 50 (94%) patients. " 02/01/1998 - "CONCLUSIONS: Long-term follow-up has confirmed the efficacy of finasteride in treating gross hematuria associated with BPH and we now recommend finasteride as first line therapy in the treatment of BPH-associated gross hematuria. " 11/01/1995 - "RESULTS: Of the 12 patients with longer than 3 months of followup (mean 14) 11 improved according to the grade of hematuria after finasteride therapy. " Order ALL the reference details at left...
2.	CreatinineIBA 01/01/2002 - "In short-term follow-up period 7 patients had normal kidney function (serum creatinine level was 99.5 micromol/l), 1 patient had impaired kidney function (serum creatinine content was 170 micromol/l), serum creatinine level improved in 4 patients and were stable in another 4 patients, 3 patients experienced relief gross hematuria. " 08/01/2003 - "RESULTS: By the end of the trial, urinary protein, hematuria, BUN and serum creatinine levels had significantly decreased in the patients of group 1 as compared to baseline. " 09/01/2000 - "After excluding the samples with hematuria (11%), the prevalence of MAU (3.0 < or = albumin-to-creatinine ratio (ACR, mg/mmol) <25.0) in the study population was 9%. " 04/01/1989 - "Because previous data had shown a greater frequency of elevated serum creatinine concentration in a population with asymptomatic microhematuria than in control subjects without hematuria, we reviewed the records of 125 patients with isolated asymptomatic microhematuria and elevated serum creatinine (AM/EC) and 83 comparison patients with no hematuria and elevated serum creatinine (NH/EC) from a previous population-based study to determine the relationship between renal parenchymal disease and isolated asymptomatic microhematuria. " 10/01/2009 - "Postembolization success was defined as symptomatic relief, resolution of hematuria, and a stable hematocrit and serum creatinine. " Order ALL the reference details at left...
3.	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/01/1996 - "RESULTS: Nonglomerular hematuria occurred in 73 of 145 patients treated with cyclophosphamide (50%). " 04/01/1990 - "Hematuria in the group as a whole was significantly associated with a lack of uroprotection, but was not associated with prior cyclophosphamide, pelvic radiotherapy, age, or bolus versus a continuous infusion schedule. " 02/01/1990 - "Hematuria in the group as a whole was not associated with prior treatment with cyclophosphamide, pelvic radiotherapy, age, or a bolus versus Cl schedule. " 07/15/1988 - "In all instances, clinical signs of hematuria and stranguria persisted after cyclophosphamide administration was discontinued. " 01/01/1987 - "A simple method of continuous bladder irrigation with two catheters is described for the management of hematuria caused by radiation or cytoxan. " Order ALL the reference details at left...
4.	Mesna (Coenzyme M)FDA LinkGeneric 03/01/1993 - "Mesna was very effective in preventing the development of hematuria." 06/01/1986 - "A significant reduction in the incidence of hematuria was observed in the patients receiving mesna. " 04/01/1990 - "The first four patients on the standard-dose study did not receive mesna because it was unavailable; three developed gross hematuria. " 01/01/2007 - "Despite the clinical use of mesna to prevent HC, a significant percent ( approximately 33%) of patients present with at last one feature of HC, mainly hematuria. " 12/01/1997 - "The combination of mesna and HBO, which act through independent mechanisms, resulted in complete protection, since mean histological scores and hematuria levels in this group were not different from controls (p >0.05). " Order ALL the reference details at left...
5.	Methylprednisolone FDA LinkGeneric 03/01/2002 - "A second biopsy was performed in 35 patients with IgA nephropathy in whom hematuria, an essential finding of IgA nephropathy, had disappeared (proteinuria also had disappeared in 23 patients) after a treatment protocol involving high doses of methylprednisolone and tonsillectomy. " 06/01/2004 - "(4) Three children with ASV died within one year after diagnosis, and two got remission and restored renal function after combined pulse therapy with methylprednisolone and cyclophosphamide (CTX), but remained to have hematuria and small amount of proteinuria after 1 and 5 year follow-up, respectively. " 02/01/2000 - "Her interstitial pneumonia improved with pulse therapy of methylprednisolone and her hematuria disappeared with mix treatment of cyclophosphamide and double filtration plasmapheresis (DFPP). " 10/01/2001 - "In the multivariate Cox regression model with 13 independent covariates, initial Scr level, histological score, tonsillectomy, and high-dose methylprednisolone therapy had a significant impact on clinical remission, whereas proteinuria, age, sex, levels of hematuria, blood pressure, conventional steroid therapy, angiotensin-converting enzyme inhibitor therapy, and cyclophosphamide therapy had no significant effect. " 01/01/2006 - "The patient presented with microscopic hematuria, proteinuria (U-pro/Cr: 4.0-4.2) and low serum complement levels (C3: 57.8 mg/dl) 3 years after IVIG treatment and was diagnosed histopathologically as having MPGN type III. Both hematuria and proteinuria significantly improved, and the serum complement level returned to a normal level following methylprednisolone pulse therapy. " Order ALL the reference details at left...
6.	Immunoglobulin A (IgA)IBA 09/01/1994 - "Hematuria was significantly greater in treatment mice than respective controls at both wk 4 and 8. Increased mesangial IgA deposition was also detectable in all treatment groups except the C57BL/6 mouse. " 11/01/1988 - "In studies done with 4 kinds of assays, IgA-IC were found more frequently and in higher titers in the 18 patients with AS with hematuria than in the 40 patients with AS without hematuria. " 05/01/1986 - "[Value of the study of IgA abnormalities in the diagnosis of hematuria in children]" 08/18/2008 - "No significant differences were seen in the disease courses, rate of gross hematuria, serum triglyceride and serum IgA level between two groups(P>0.05).Renal pathological investigation showed the chronic lesions were dominated in elder group. " 06/01/2005 - "The number of lymphocytes correlated significantly with serum IgA and COX-2-expression with serum IgA and the degree of hematuria. " Order ALL the reference details at left...
7.	nuclear matrix protein 22IBA 02/01/2002 - "False-positive results of the NMP22 test due to hematuria." 04/01/2008 - "Group 2:15 patients with history of hematuria underwent cystoscopy and NMP22 BladderChek. " 02/01/2002 - "The source of NMP22 in isolated hematuria remains to be elucidated. " 02/01/1999 - "Materials and methods: NMP22 values in voided urines were determined on 90 patients (81 males, 14 females) with macro or microscopical hematuria, using the NMP22 test-kit (Matritech) based on an enzyme-linked immuno-sorbant assay. " 05/01/1997 - "Urinary NMP22 values were determined for 183 patients with microscopic hematuria by use of a UNMP22 Test kit, which is based on an enzyme-linked immunosorbent assay. " Order ALL the reference details at left...
8.	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/01/2002 - "Rapidly progressing renal damage was found with mild microscopic hematuria and positive ANCA. " 05/15/1997 - "Testing for hematuria and early transplant biopsies, and possibly monitoring of ANCA titers, are essential, but pretransplant ANCA titers have no predictive value in asymptomatic patients. " 10/01/2005 - "Laboratory data demonstrated renal dysfunction with hematuria and proteinuria and serum MPO-ANCA was also elevated. " 01/01/2005 - "On laboratory evaluation, her level of MPO-ANCA was 422 EU, and urinalysis revealed proteinuria and hematuria. " 01/01/2002 - "With hematuria, the leukocyte infiltration in the capillary lumen and the change in epithelial cells of Bowman's capsules would be histological findings suggesting ANCA-associated nephritis. " Order ALL the reference details at left...
9.	Formaldehyde (Formol)IBA 04/01/1989 - "Increasing concentrations of formalin slightly improved effectiveness of therapy and reduced the rate of recurrence of hematuria. " 11/01/1998 - "After intravesical formalin instillation was performed twice, the hematuria ceased completely." 03/01/1994 - "Intravesical formalin appears to be the most effective regimen in controlling profuse, persistent hematuria." 03/01/1994 - "Six patients required intravesical formalin instillation to control the hematuria. " 04/01/1989 - "Effectiveness of therapy, rate of recurrence of hematuria, morbidity and mortality were analyzed with respect to concentration of formalin and to the etiology of hematuria. " Order ALL the reference details at left...
10.	AnticoagulantsIBA 11/01/2004 - "Timely and thorough evaluation of hematuria in patients taking anticoagulants is necessary to identify and treat clinically important pathology." 09/01/1987 - "The results suggest that IV urography and cystography are warranted in patients who take anticoagulants and who have gross hematuria." 05/18/1987 - "[Hematuria during treatment with anticoagulants]" 07/28/1977 - "Hematuria in patients on anticoagulants." 11/01/2004 - "Although this patient was considered low risk for the development of bladder cancer and was taking anticoagulants, the presence of hematuria was indicative of underlying pathology. " Order ALL the reference details at left...

Therapies and Procedures

1.	Aftercare (After-Treatment) 04/01/1995 - "A few months after treatment, microscopic hematuria disappeared and hypocomplementemia improved. " 11/01/2009 - "The incidence of blood pressure and microscopic hematuria grading increment at 2 weeks after treatment was 6.8% and 13.8%, respectively. " 11/01/2005 - "Severe gross hematuria completely subsided after treatment and no serious complications are noted during 2- or 3-year follow-up; moreover, all patients have good physical development." 01/01/2001 - "Since the use of HBO2 therapy has not been previously reported in this situation, we met with some hesitation from the HBO2 therapy department After reviewing the literature and discussing the case, a medical panel reached a consensus to allow us to commence the treatment The patient had a remarkable response, and remains without hematuria 6 mo. after treatment." 05/01/1995 - "Hematuria resolved in more than 90% of the patients after treatment. " Order ALL the reference details at left...
2.	Tonsillectomy 02/01/2007 - "CONCLUSION : Tonsillectomy was effective in improving hematuria. " 01/01/2007 - "The notion that tonsillectomy not only helps to prevent episodic macroscopic hematuria in the short-term but also gives long-term renal protection in IgAN is supported by two large retrospective studies from Japan. " 12/01/2004 - "These results suggest that the reduced number of activated mesangial cells and macrophages may be involved in the improvement of hematuria after tonsillectomy. " 01/01/1999 - "Tonsillectomy for asymptomatic isolated hematuria." 12/29/1996 - "Furthermore, tonsillectomy stopped gross hematuria appearing in the acute exacerbation of the disease in more than two-thirds of patients. " Order ALL the reference details at left...
3.	Stents 09/01/2009 - "Although the cat showed 2 days of transient hematuria after the stent placement, no further obstruction was occurred after the stent placement. " 08/01/2009 - "Following placement of a vascular endoprosthesis and a double J stent gross hematuria developed. " 01/01/2009 - "CASE PRESENTATION: We report a case of a patient with intermittent gross hematuria after previous abdominal surgery, radiotherapy and indwelling ureteric stents. " 04/01/2008 - "The patient's ureteral stent has been replaced every 2 months since his discharge without recurrence of hematuria." 08/01/2007 - "Fifteen years after the operation, gross hematuria occurred from the left ureteral orifice when exchanging the left ureteral double J-stent. " Order ALL the reference details at left...
4.	Drug Therapy (Chemotherapy) 07/01/2006 - "These markers include some that can be applied during the diagnostic work-up of symptoms (e.g., hematuria), those under surveillance for recurrence of superficial disease and forecasting long-term prognosis, or response to chemotherapy. " 01/01/1989 - "Review of reported renal biopsies identifies mesangial glomerulopathy as a common finding in RA patients without associated drug therapy and that it is frequently associated with hematuria in nonrheumatoid patients. " 04/01/2008 - "The other had microscopic hematuria 3 years before the onset of non-Hodgkin lymphoma, and hematuria continued during chemotherapy. " 12/01/2001 - "Proteinuria (>30 mg/dL) and hematuria were not identified in any of the chemotherapy courses. " 03/01/1999 - "The patient was undergoing chemotherapy for her recurrent ovarian tumor when she was referred to the urology service for microscopic hematuria. " Order ALL the reference details at left...
5.	Intravesical Administration 06/01/1993 - "The factors assessed in the present analysis included sex, age, interval between initial symptoms and first consultation, presence of hematuria, bladder irritability, tumor shape, tumor base configulation size, number, grade, stage, initial treatment, bladder instillation and medication. " 08/01/1995 - "Seven-day courses of 500 micrograms prostaglandin E1 (PGE1) bladder instillations was initiated to control hematuria in these 6 patients. " 02/01/1993 - "A prospective study was done to evaluate the efficacy and safety of intravesical instillation of 1% alum solution in 12 cases of hematuria of vesical origin, uncontrolled by saline irrigation for 24 hours via a 3-way Foley catheter. " 01/01/1992 - "A comparative study of intravesical instillation of 15(s) 15 Me alpha and alum in the management of persistent hematuria of vesical origin." 11/01/1973 - "Intravesical instillation of formalin for the management of intractable hematuria." Order ALL the reference details at left...

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