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Fatal rickettsial meningitis in Hong Kong: a need for rapid laboratory diagnosis.

Abstract
A 22-year-old Chinese male, investigated elsewhere for fever and myalgia, was transferred to our hospital drowsy, unresponsive to commands and with a petechial rash. Partially treated meningococcal meningitis was suspected and high-dose antibiotics were immediately started. Rising Weil-Felix titres occurred too late for anti-rickettsial therapy to prevent a fatal outcome. Subsequent specific serology showed rising titres against Rickettsia conori. The desirability of more rapid and reliable methods of laboratory diagnosis of rickettsial infection is evident.
AuthorsR P Young, M Ip, D C Bassett
JournalScandinavian journal of infectious diseases (Scand J Infect Dis) Vol. 27 Issue 5 Pg. 527-8 ( 1995) ISSN: 0036-5548 [Print] England
PMID8588149 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Antibodies, Bacterial
Topics
  • Adult
  • Anti-Bacterial Agents (therapeutic use)
  • Antibodies, Bacterial (blood)
  • Fatal Outcome
  • Hong Kong
  • Humans
  • Male
  • Meningitis, Bacterial (diagnosis, drug therapy, immunology)
  • Rickettsia (immunology)
  • Rickettsia Infections (diagnosis, drug therapy, immunology)

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