[The treatment of postoperative pain in obstetrical-gynecologic surgery. A comparative study between ST-679 and paracetamol].

Abstract

In double-blind conditions, ST-679 (a single oral 1200 mg dose in 20 patients), or paracetamol (a single oral dose of 1000 mg in 20 patients) was administered to forty patients who presented pain as a result of obstetrical-gynecological surgery. The study proposed to evaluate the analgesic efficacy and tolerability of ST-679, a new non-steroid antiphlogistic drug, as compared to a reference drug amply utilized in clinical practice such as paracetamol. The average estimation of tolerability, with regard to paracetamol, was significantly in favor of ST-679.

• Authors: C Nappi, G Nolfe, M La Pinta, G Colace, C Ruotolo, P Affinito
• Journal: La Clinica terapeutica (Clin Ter) Vol. 142 Issue 1 Pt 2 Pg. 47-52 (Jan 1993) ISSN: 0009-9074 [Print] Italy
• Vernacular Title: Trattamento del dolore postoperatorio nella chirurgia ostetrico-ginecologica. Studio comparativo tra ST-679 e paracetamolo.
• PMID: 8472521 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Pyrroles
• ST 679
• Acetaminophen
• Glycine

Topics

• Acetaminophen (therapeutic use)
• Administration, Oral
• Adolescent
• Adult
• Aged
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Double-Blind Method
• Drug Tolerance
• Female
• Genital Diseases, Female (surgery)
• Glycine (analogs & derivatives, therapeutic use)
• Humans
• Middle Aged
• Pain Measurement
• Pain, Postoperative (drug therapy)
• Pregnancy
• Pregnancy Complications (surgery)
• Pyrroles (therapeutic use)