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Elevated estrogen 16 alpha-hydroxylase activity: is this a genotoxic or nongenotoxic biomarker in human breast cancer risk?

AuthorsD W Nebert
JournalJournal of the National Cancer Institute (J Natl Cancer Inst) Vol. 85 Issue 23 Pg. 1888-91 (Dec 01 1993) ISSN: 0027-8874 [Print] United States
PMID8230275 (Publication Type: Comment, Editorial, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Biomarkers, Tumor
  • Receptors, Estrogen
  • Estradiol
  • Cytochrome P-450 Enzyme System
  • Steroid Hydroxylases
  • Aryl Hydrocarbon Hydroxylases
  • Steroid 16-alpha-Hydroxylase
Topics
  • Aryl Hydrocarbon Hydroxylases
  • Biomarkers, Tumor (metabolism)
  • Breast Neoplasms (enzymology)
  • Cytochrome P-450 Enzyme System (metabolism)
  • Estradiol (metabolism)
  • Female
  • Humans
  • Oxidation-Reduction
  • Polymorphism, Genetic (physiology)
  • Receptors, Estrogen (metabolism)
  • Risk Factors
  • Steroid 16-alpha-Hydroxylase
  • Steroid Hydroxylases (metabolism)

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