Neurotensin-like immunoreactivity in locust supraesophageal ganglion and optic lobes.
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| Abstract |
A substance immunoreactive to antibodies directed against bovine neurotensin (NT) was localized in neurons in the supraesophageal ganglion (SEG) and optic lobes of larval and adult Locusta migratoria L. Two large somata were located in the caudal cortex, ventral to the calyces and symmetrical to the median of the SEG. Four smaller somata also in the caudal cortex were located as two symmetrical pairs at the level of the central body. These somata formed a diffuse network of varicose fibers from the superior lateral to the ventro-lateral protocerebrum between the pedunculi and frontal cortical region. Some fibers crossed the median to the contralateral sides of the SEG. Another pair of immunoreactive somata whose terminating processes remained unclear was found at the level of the antennal lobes. Intrinsic networks of fibers were labeled in the accessory medulla and in layer 4/5 of the medulla. These fibers originated from 8-10 small somata near the dorso-frontal rim of the medulla. All larval stages contained these NT-like immunoreactive structures. Results from isoelectric focusing and press-blot analysis of SEG homogenates, synthetic neurotensin and neurotensin fragments indicate that this substance is similar to bovine neurotensin(1-13).
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| Authors | J Ammermüller, M Oltrogge, U Janssen-Bienhold |
| Journal | Brain research (Brain Res) Vol. 636 Issue 1 Pg. 40-8 (Feb 04 1994) ISSN: 0006-8993 [Print] Netherlands |
| PMID | 8156409 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't) |
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