Case report: the effect of a Chinese herbal medicine, BG-104 in two HIV positive hemophiliacs.

Abstract

The BG-104, a Chinese herbal medicine, has been reported to restore decreased plasma superoxide scavenging activity. This report showed in vivo effect of BG-104 on two patients with hemophilia A infected with human immunodeficiency virus by infusions of the concentrated Factor VIII. Both patients, showed a peripheral CD4+ T-lymphocytopenia for more than half a year. BG-104 was administered daily and follow-up observations were continued for 3 years. The number of CD4+ T-lymphocytes remained relatively constant during BG-104 treatment without disease progression.

• Authors: S Arimori, H Nozaki, K Morita, K Arimori
• Journal: Biotherapy (Dordrecht, Netherlands) (Biotherapy) Vol. 7 Issue 1 Pg. 55-7 ( 1993) ISSN: 0921-299X [Print] Netherlands
• PMID: 7915126 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antioxidants
• CD8 Antigens
• Drugs, Chinese Herbal
• Free Radical Scavengers
• BG 104

Topics

• Adult
• Antioxidants (therapeutic use)
• CD4-Positive T-Lymphocytes
• CD8 Antigens (analysis)
• Drugs, Chinese Herbal (therapeutic use)
• Flow Cytometry
• Follow-Up Studies
• Free Radical Scavengers
• HIV Seropositivity (complications, drug therapy)
• Hemophilia A (blood, complications, drug therapy, microbiology)
• Humans
• Leukocyte Count
• Male
• T-Lymphocytes (immunology)
• T-Lymphocytopenia, Idiopathic CD4-Positive (prevention & control)