[Morphological characteristics of tumor tissue explants cultured in diffusion chambers].

Abstract

With cultivation of explants of different human malignant tumors in diffusion chambers at the same study terms, differences in the ratio of epithelial-like and fibroblast-like cell growth were noticed with marked degeneration changes in one of these cel types, and in the ability to form spheroids from epithelial-like cells. These data are discussed in connection with the optimal time of obtaining the cell material ready for a further cultivation of cell suspensions, with the aim to prepare autovaccines for infection of patients with malignant tumors.

• Authors: L V Iakhimovich, R A Semenova-Kobzar', Iu A Umanskiĭ
• Journal: Tsitologiia (Tsitologiia) Vol. 23 Issue 11 Pg. 1304-9 (Nov 1981) ISSN: 0041-3771 [Print] Russia (Federation)
• Vernacular Title: Morfologicheskaia kharakteristika éksplantatov opukholevykh tkaneĭ, kul'tiviruemykh v diffuzionnykh kamerakh.
• PMID: 7324169 (Publication Type: English Abstract, Journal Article)

Topics

• Adenocarcinoma (pathology)
• Animals
• Carcinoma, Bronchogenic (pathology)
• Carcinoma, Squamous Cell (pathology)
• Cell Transformation, Neoplastic (pathology)
• Culture Techniques (instrumentation)
• Esophageal Neoplasms (pathology)
• Humans
• Lung Neoplasms (pathology)
• Mice
• Neoplasm Transplantation
• Neoplasms (pathology)
• Rectal Neoplasms (pathology)