[Changes in the T- and B-lymphocyte ratio in bone sarcoma patients before and after carminomycin treatment].

Abstract

The clinical ratio of T- and B-lymphocytes in the peripheral blood of patients with osteogenic sarcoma and Ewing's sarcoma was studied. Significant changes in the ratio of T- and B-cells was found in the patients in the stage of generalization with metastases to the bones and lungs. During the treatment with carminomycin the relative number of T-cells reached the values close to the normal. The total number of lymphocytes in the blood and the absolute content of T- and B-cells in some patients remained decreased for a long period of time.

• Authors: A E Vatin, V A Bizer
• Journal: Antibiotiki (Antibiotiki) Vol. 25 Issue 11 Pg. 864-7 (Nov 1980) ISSN: 0003-5637 [Print] Russia (Federation)
• Vernacular Title: Izmenneiiia v sootnoshenii T- i B-limfotsikov u bol'nykh sarkomami kosteĭ do i posle lecheniia karminomitsinom.
• PMID: 6969572 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Carubicin
• Daunorubicin

Topics

• Adolescent
• Adult
• B-Lymphocytes (drug effects)
• Bone Neoplasms (drug therapy)
• Carubicin (therapeutic use)
• Child
• Child, Preschool
• Daunorubicin (analogs & derivatives)
• Humans
• Leukocyte Count
• Osteosarcoma (drug therapy)
• Rosette Formation
• Sarcoma, Ewing (drug therapy)
• T-Lymphocytes (drug effects)
• Time Factors