Pseudomembranous colitis in a patient on rifampicin and ethambutol.

Abstract	A fifty-seven year old male with renal tuberculosis developed pseudomembranous colitis on rifampicin and ethambutol. Diarrhoea occurred within a week, and six weeks after commencing these antituberculous agents he developed typical sigmoidoscopic and biopsy findings. Withdrawal of the drugs led to rapid recovery. Repeated challenge testing indicated that the symptoms were worse when rifampicin was given, but a test dose of ethambutol also produced temporary aggravation of the diarrhoea.
Authors	H J Moriarty, B A Scobie
Journal	The New Zealand medical journal (N Z Med J) Vol. 91 Issue 658 Pg. 294-5 (Apr 23 1980) ISSN: 0028-8446 [Print] New Zealand
PMID	6930008 (Publication Type: Case Reports, Journal Article)
Chemical References	Ethambutol Rifampin
Topics	Biopsy Drug Therapy, Combination Enterocolitis, Pseudomembranous (chemically induced, pathology) Ethambutol (adverse effects) Humans Male Middle Aged Rifampin (adverse effects) Tuberculosis, Renal (drug therapy)

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