[Retrospective study of the evaluation of peptic ulcer recurrence after 4 weeks of pirenzepin (Gastrozepin) treatment].

Abstract

In a recent study the effect of Pirencepine in the treatment of peptic gastric or duodenal ulcers was reported. Relapse rates were investigated one year after the end of these studies. The patients did not receive any treatment to prevent ulcer recurrence. It was found that 20% of the patients who have had ulcer healing after 4 weeks of Pirenzepine treatment, exhibited recurrent ulcers. The relapse rate was higher in these patients who had one or more ulcers prior to the Pirencepine studies. From the results of the present investigation it is concluded that Pirenzepine has a more beneficial effect in the treatment of peptic ulcers than placebo as observed in other studies.

• Authors: F Krempler, F Sandhofer, A Kalk
• Journal: Wiener medizinische Wochenschrift (1946) (Wien Med Wochenschr) Vol. 133 Issue 21 Pg. 553-7 (Nov 15 1983) ISSN: 0043-5341 [Print] Austria
• Vernacular Title: Retrospektive Untersuchung zur Erfassung von Rezidiven peptischer Ulzera nach einer 4wöchigen Behandlung mit Pirenzepin (Gastrozepin).
• PMID: 6689235 (Publication Type: English Abstract, Journal Article)

Chemical References

• Benzodiazepinones
• Pirenzepine

Topics

• Benzodiazepinones (therapeutic use)
• Humans
• Peptic Ulcer (drug therapy)
• Pirenzepine
• Recurrence
• Retrospective Studies