Abstract |
Two hundred and seventeen patients between 6 and 12 years of age suffering from acute cough took part in a randomized, single-blind study comparing ' Pholcolix' and ' Actifed' Compound. No significant difference in efficacy was demonstrated but analysis of palatability components (taste, smell, aftertaste and feeling in the mouth) showed numerical superiority for ' Pholcolix' for all parameters, with a high degree of significance for overall taste. ' Pholcolix' caused significantly fewer side-effects, with ' Actifed' Compound causing markedly more drowsiness after daytime dosage.
|
Authors | G Jaffé, J J Grimshaw |
Journal | Current medical research and opinion
(Curr Med Res Opin)
Vol. 8
Issue 8
Pg. 594-9
( 1983)
ISSN: 0300-7995 [Print] England |
PMID | 6653137
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Antitussive Agents
- Drug Combinations
- Pyridines
- pseudoephedrine, triprolidine drug combination
- Triprolidine
- Phenylpropanolamine
- Acetaminophen
- Pseudoephedrine
- pholcolix
- Ephedrine
- Codeine
|
Topics |
- Acetaminophen
(adverse effects, therapeutic use)
- Antitussive Agents
(therapeutic use)
- Child
- Codeine
(adverse effects, analogs & derivatives, therapeutic use)
- Cough
(drug therapy)
- Drug Combinations
(adverse effects, therapeutic use)
- Ephedrine
(adverse effects, therapeutic use)
- Female
- Humans
- Male
- Patient Acceptance of Health Care
- Phenylpropanolamine
(adverse effects, therapeutic use)
- Pseudoephedrine
- Pyridines
(therapeutic use)
- Random Allocation
- Sleep Stages
(drug effects)
- Triprolidine
(adverse effects, therapeutic use)
|