[Reduction of the incidence of suppurative complications after mitral commissurotomy through the use of pentoxyl and methyluracil].

Abstract

Clinico-experimental study of the pentoxyl and methyluracil effect upon the natural resistance in mitral stenosis cases is presented together with the findings obtained in the experiments dealing with the healing of the wounds infected with pathogenic staphylococcus. All the control animals developed subcutaneous abscesses leading to the separation of the wound margins. The inflammation of the wound was less pronounced in the animals treated with pentoxyl and methyluracil. The use of pyrimidin derivatives before and during operation and postoperatively resulted in the decrease of the incidence of postoperative suppurative complications.

• Authors: A S Iarygin, R M Markov
• Journal: Vestnik khirurgii imeni I. I. Grekova (Vestn Khir Im I I Grek) Vol. 120 Issue 2 Pg. 19-23 (Feb 1978) ISSN: 0042-4625 [Print] Russia (Federation)
• Vernacular Title: O sokrashchenii gnoĭnykh oslozhneniĭ posle mitral'noĭ komissurotomii primeneniem pentoksila i metiluratsila.
• PMID: 644774 (Publication Type: English Abstract, Journal Article)

Chemical References

• Uracil

Topics

• Adolescent
• Adult
• Animals
• Drug Evaluation
• Humans
• Middle Aged
• Mitral Valve Stenosis (surgery)
• Postoperative Care
• Preoperative Care
• Rabbits
• Surgical Wound Infection (prevention & control)
• Uracil (analogs & derivatives, therapeutic use)