The failure of conventional drug therapy in the management of infantile colic.

Abstract	During five years, 97 young infants with colic were studied. One of us (J. C. O'D.) compared homatropine methylbromide plus phenobarbital in a 20% alcohol solution, and all of the individual components of that solution, to see which was most effective in the symptomatic relief of colic. Regardless of the child's age on entry into the study, conditions in no treatment group improved more rapidly than in those treated with a placebo.
Authors	J C O'Donovan, A S Bradstock Jr
Journal	American journal of diseases of children (1960) (Am J Dis Child) Vol. 133 Issue 10 Pg. 999-1001 (Oct 1979) ISSN: 0002-922X [Print] United States
PMID	582880 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
Chemical References	Placebos Tropanes Ethanol Phenobarbital
Topics	Colic (drug therapy) Double-Blind Method Drug Therapy, Combination Ethanol (therapeutic use) Female Humans Infant Infant, Newborn Male Phenobarbital (therapeutic use) Placebos Tropanes (therapeutic use)

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