[Repair of fundo-antral gastric fistula by homologous and heterologous fundo-antral tranplansts in adult rats].

Abstract

Use of fundo-antral gastric transplants excised from Rat or guinea-pig stomach in order to repair fundo-antral fistula was well tolerated by adult Rats and compatible with a normal survival. In 90% of homologous transplantation, and 70% of heterologous transplantation, no brutal and mortal rejection of transplant was observed. The transplant did not regenerate, but its corpse was not eliminated, and remained united to the wall of the receiver's stomach, and infiltrated with lymphocytes. We explain the benignity of immunologic reaction in evoking the role of the liver which acts as a filter in sequestering a great part of antigens, and so moderating the antibody response by the spleen and lymphoid system.

• Authors: H Le Van, N Khieu, T N Duong
• Journal: Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles (C R Acad Hebd Seances Acad Sci D) Vol. 284 Issue 18 Pg. 1823-5 (May 09 1977) France
• Vernacular Title: Réparation d'une fistule fondo-antrale gastrique par un transplant fondo-antral homologue et hétérologue chez le rat adulte.
• PMID: 408025 (Publication Type: English Abstract, Journal Article)

Topics

• Animals
• Gastric Fistula (surgery)
• Graft Survival
• Guinea Pigs
• Male
• Rats
• Stomach (transplantation)
• Transplantation, Heterologous
• Transplantation, Homologous