Abstract |
Variations in the upper limit of normal total serum IgE have been reported: they can range from 150 to 1,000 UI/ml; but the usually accepted upper limit is between 150 and 300 UI/ml. In this study we measured the total serum IgE levels (RIST-Pharmacia) in 69 randomly selected control subjects; 38 had no previous history of atopic or parasitic disease. The normal values observed were 7-460 UI/ml for the whole of the control group (10th-90th percentiles) and 0.5-540 UI/ml for the 38 selected subjects (5th-95th percentiles). Logarithmic conversion is compulsory in order to obtain a gaussian distribution. This enables 80 p. 100 of the control subjects to be grouped within 4-450 UI/ml or 90 p. 100 of the selected subgroup within the range of 1.5-677 UI/ml. As many allergic patients have a normal serum IgE level and a number of non-allergic diseases may be associated with an increased serum IgE level, the diagnostic importance of this investigation is limited. The cost-effectiveness is very low and raises the problem of using this test in everyday practice.
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Authors | J Laurent, C Noirot, J C Ansquer, G Laurent, S Kestenbaum, G Lagrue |
Journal | Annales de medecine interne
(Ann Med Interne (Paris))
Vol. 136
Issue 5
Pg. 419-22
( 1985)
ISSN: 0003-410X [Print] France |
Vernacular Title | Comment définir le taux normal des IgE sériques chez l'adulte? |
PMID | 4062142
(Publication Type: English Abstract, Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Female
- Humans
- Hypersensitivity
(immunology)
- Immunoglobulin E
(analysis)
- Male
- Middle Aged
- Obesity
(immunology)
- Radioimmunosorbent Test
- Reference Values
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