Immunoglobulin E (IgE)

Subscribe to Selected New Research on Immunoglobulin E

14572 relevant articles (403 outcomes, 1468 trials/studies) found for this Bio-Agent

Description: An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).

Also Known As:

IgE; E, Immunoglobulin; Immunoglobulins, E

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 58433

Globulins: 305

Serum Globulins: 74

Immunoglobulins: 20136

Antibodies: 77322

Immunoglobulin Isotypes: 348

Immunoglobulin E: 14572

pentigide: 28

IGE class-specific suppressor factor: 2

Immunoglobulin epsilon-Chains: 2

IGE decapeptide: 1

aspartyl-seryl-aspartyl-glycyl-lysine

IgE octapeptide (497-504)

igercine

Experts

1.	Park, Hae-Sim: 11 articles (08/2008 - 06/2002)
2.	Wahn, U: 9 articles (10/2008 - 05/2000)
3.	Valenta, Rudolf: 8 articles (09/2008 - 04/2002)
4.	Ring, Johannes: 8 articles (01/2008 - 01/2003)
5.	Durham, Stephen R: 8 articles (09/2007 - 05/2002)
6.	Gould, Hannah J: 7 articles (03/2008 - 04/2003)
7.	Vieths, Stefan: 7 articles (01/2008 - 01/2003)
8.	Alenius, Harri: 7 articles (12/2005 - 01/2002)
9.	Johansson, S G O: 6 articles (09/2008 - 05/2003)
10.	Niggemann, Bodo: 6 articles (08/2008 - 02/2004)

Related Diseases

1.	Hypersensitivity (Allergy) 11/01/2000 - "4) Skin test and/or IgE RAST showed positive results in most cases, suggesting that the response itself is linked to type I allergic reaction. " 11/01/1990 - "Sera from 33 patients with mold allergy proven by bronchial provocation were analyzed for specific IgE against six mold species comparing an improved Phadebas RAST with four other techniques. " 10/01/2003 - "There is good concurrence between skin testing techniques and various serum measures of specific IgE, and both methods can be used effectively for screening inhalant allergy, although per-test costs for in vitro methods remain higher than comparable costs for skin testing [28]. " 03/01/1992 - "We conclude, that hyperosomolar media selectively enhance IgE-receptor-mediated HR. The use of hyperosmolar media may therefore be beneficial in a diagnostic application of washed blood HR assays used in allergy diagnosis." 06/01/1990 - "Positive results require a confirmatory medical history, whereas negative results exclude IgE-mediated allergy with a high degree of reliability. " Order ALL the reference details at left...
2.	Asthma (Bronchial Asthma) 03/01/1999 - "CONCLUSION: This study suggests that (1) the percentage of CD4+, CD8+, or IL-2R+ lymphocytes in peripheral blood was significantly elevated during acute attacks and returned to normal ranges after complete remission was achieved; (2) plasma soluble IL-2R is a sensitive marker for asthma activity; and (3) atopic asthmatic children seem to have a hereditary predisposition of having higher levels of soluble IL-2R in asthma attacks, coinherited with the trait of IgE." 07/01/2000 - "I have three objectives: (1) review T cell differentiation leading to the Th1/Th2 paradigm; (2) evaluate the increased prevalence of atopy, including asthma, as a consequence of a Th2-dominated immune system; (3) relate the high prevalence of asthma in inner city United States black children to the relatively recent migration of their ancestors from tropical regions of Africa, where genetically biased Th2-dependent IgE responses may be important in protection against high burdens of parasitic worms." 02/01/2007 - "In the 18 subjects no longer responsive to TDI, 8 had still features of asthma: their symptom and medication score had improved significantly, but FEV(1), PD(20) and serum IgE had not significantly changed; the other ten patients no longer reactors to TDI were also asymptomatic and their PD(20) had become normal. " 09/01/2000 - "The following features were recognized among patients with bronchial asthma induced by contact with hamsters: 1) earlier onset of symptoms than for keeping other household pets, at an average of 14.7 months or within 12 months in 78% of the cases following the start of pet keeping; 2) adults ranging from their late 30s to 40s who have children of primary school age; 3) dwelling in apartments; 4) relatively high level of serum IgE and ECP; 5) positive for both immediate and late type asthmatic responses on an inhaling induction test; and 6) rapid remission after the cessation of pet keeping." 08/25/2000 - "These results indicate that the efficacy of TEI-9874 on the asthmatic response is mainly mediated by the suppression of allergen-specific IgE production and TEI-9874 appears to be a good candidate as therapy for IgE-mediated allergic asthma." Order ALL the reference details at left...
3.	Infection 08/01/1997 - "Total IgE was highly elevated in progressive AE cases (7/11), but not in the cases with eliminated infection or regression. " 01/01/1976 - "Nippostrongylus brasiliensis infection was found to be highly effective in inducing a carrier-specific enhancing effect on primary and secondary antihapten IgE antibody response in the rat, when animals were immunized i.p. " 12/01/1990 - "Anti-IL-5-treated vaccinated mice showed a complete ablation of circulating as well as tissue eosinophils present in inflammatory reactions to migrating schistosomula in the skin and lungs but nevertheless eliminated challenge infections as effectively as vaccinated animals treated with a control mAb. Similarly, treatment of vaccinated mice with an anti-IL-4 mAb markedly reduced serum IgE although failing to diminish immunity. " 01/01/1986 - "The finding of IgE in feces from individuals with intestinal ascaris infection and nearly complete disappearance of IgE in feces after successful therapy is further evidence of local production of IgE in the gut mucosa." 05/01/2003 - "Those with high levels of IgE had significantly greater lower respiratory tract symptom scores during the initial 4 days of the infection than the low IgE group. " Order ALL the reference details at left...
4.	Atopic Dermatitis (Atopic Eczema) 01/01/2002 - "The combination of the local disinfection therapy against Staphylococcus aureus with the conventional therapy for atopic dermatitis has been widely used, and the improvement in skin lesions has been reported to be associated with a remarkable decrease in IgE levels and reagin antibody titers. " 07/01/1987 - "Studies performed on patients with atopic dermatitis have shown high IgE levels, eosinophils and T4 counts, and a marked decrease in T8 suppressor cells in peripheral blood. " 10/01/1995 - "In both groups, atopic eczema improved significantly and progressively, and a downward trend was found in serum total and milk-specific IgE concentrations, proving the efficacy of both formulas. " 12/01/1983 - "Six of seven patients with moderate to severe atopic dermatitis and IgE levels of 1339 to 24,261 IU/ml had less than 0.1% T epsilon cells and significantly fewer T gamma cells (3.1% +/- 2.7, p less than 0.01) than the nonatopic control donors and the atopic donors in remission. " 12/01/2004 - "In vivo transfection of a cis element 'decoy' against signal transducers and activators of transcription 6 (STAT6)-binding site ameliorates IgE-mediated late-phase reaction in an atopic dermatitis mouse model." Order ALL the reference details at left...
5.	Anaphylaxis (Anaphylactic Shock) 12/01/1998 - "CONCLUSION: The results indicate that LEA confers protection against anaphylaxis to mice due to their ability to induce a high IFN-gamma:IL-4 ratio which may lead to decreased synthesis of IgE and reduced histamine release on challenge with FA." 01/01/1984 - "These findings indicate that treatment with nonspecific IgE prior to sensitization is effective in blocking anaphylactic reactions but competition with cell-bound IgE in sensitized animals requires prolonged administration of relatively large quantities of 'nonsense' IgE." 04/01/1987 - "Anaphylaxis to muscle relaxants appears to be a very useful model to study the IgE-dependent mechanisms of mediator release in humans. " 11/01/1995 - "[Efficacy of the artificial ventilation for the treatment of IgE-mediated anaphylactic shock in dog]" 07/01/2009 - "The objective of the present study was to assess the effects of Enterococcus sp. strain TN-3 isolated from deep seawater on inhibition of eosinophil accumulation, IgE production and active cutaneous anaphylaxis (ACA). " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Antibodies
2.	Immunoglobulin G (IgG)
3.	Antigens
4.	Immunoglobulin E (IgE)
5.	Allergens
6.	omalizumab (Xolair)
7.	anti-IgE
8.	Immunoglobulin A (IgA)
9.	Interleukin-4 (Interleukin 4)
10.	Cytokines

Related Therapies and Procedures

1.	Immunotherapy
2.	Oral Administration
3.	Drug Therapy (Chemotherapy)
4.	Intranasal Administration
5.	Injections

Best Treatments:
Research Summary Report
on Hypersensitivity

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 1015 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>