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Immunoglobulin E (IgE)

An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).
Also Known As:
IgE; Immunoglobulins, E
Networked: 28505 relevant articles (952 outcomes, 2890 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Valenta, Rudolf: 152 articles (10/2022 - 01/2002)
2. Sampson, Hugh A: 90 articles (01/2022 - 04/2002)
3. Platts-Mills, Thomas A E: 69 articles (10/2022 - 03/2002)
4. Park, Hae-Sim: 62 articles (02/2022 - 05/2002)
5. Valenta, R: 58 articles (01/2019 - 01/2000)
6. Bachert, Claus: 57 articles (01/2022 - 11/2002)
7. van Hage, Marianne: 54 articles (06/2022 - 07/2005)
8. Vieths, Stefan: 54 articles (01/2021 - 01/2002)
9. Hamilton, Robert G: 53 articles (06/2022 - 08/2002)
10. Galli, Stephen J: 49 articles (12/2021 - 06/2002)

Related Diseases

1. Asthma (Bronchial Asthma)
01/01/2018 - "For diagnosis of baker's asthma, a whole wheat extract is still the best option for specific IgE determination. "
03/01/1999 - "This study suggests that (1) the percentage of CD4+, CD8+, or IL-2R+ lymphocytes in peripheral blood was significantly elevated during acute attacks and returned to normal ranges after complete remission was achieved; (2) plasma soluble IL-2R is a sensitive marker for asthma activity; and (3) atopic asthmatic children seem to have a hereditary predisposition of having higher levels of soluble IL-2R in asthma attacks, coinherited with the trait of IgE."
01/01/2012 - "Blood immunoglobulin E levels were significantly increased in the asthma group, and blood eosinophils were significantly elevated in the complete asthma remission, symptomatic remission and asthma groups compared with controls. "
07/01/2000 - "I have three objectives: (1) review T cell differentiation leading to the Th1/Th2 paradigm; (2) evaluate the increased prevalence of atopy, including asthma, as a consequence of a Th2-dominated immune system; (3) relate the high prevalence of asthma in inner city United States black children to the relatively recent migration of their ancestors from tropical regions of Africa, where genetically biased Th2-dependent IgE responses may be important in protection against high burdens of parasitic worms."
11/01/2021 - "The prevalence of CSU recurrence after a full remission is significantly higher among patients with existing bronchial asthma, increased levels of total IgE, and autoimmunity. "
2. Hypersensitivity (Allergy)
3. Food Hypersensitivity (Food Allergy)
4. Atopic Dermatitis (Atopic Eczema)
5. Infections

Related Drugs and Biologics

1. Allergens
2. Omalizumab (Xolair)
3. Immunoglobulin E (IgE)
4. Immunoglobulin G (IgG)
5. Antibodies
6. Cytokines
7. Antigens
8. Monoclonal Antibodies
9. Interleukin-4 (Interleukin 4)
10. Interleukin-13

Related Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Oral Administration
4. Drug Therapy (Chemotherapy)
5. Injections