[Effect of phosphemide in combination with dexamethasone on DNA structure in sarcoma 45].

Abstract

It is shown that under the influence of phosphemide in combination with dexamethasone some characteristics of tumour DNA (content of 5 methyl cytosine, temperature, interval and enthalpy of melting) approximate the corresponding characteristics of DNA of healthy animals' liver better than under the influence of phosphemide only.

• Authors: Iu S Babaian, L L Aslanian, G V Ananian, D V Garibian
• Journal: Biofizika (Biofizika) 1985 May-Jun Vol. 30 Issue 3 Pg. 414-7 ISSN: 0006-3029 [Print] Russia (Federation)
• Vernacular Title: Vliianie fosfemida v sochetanii s deksametazonom na strukturu DNK sarkomy 45.
• PMID: 4027269 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents
• Aziridines
• Azirines
• DNA, Neoplasm
• DNA, Single-Stranded
• 5-Methylcytosine
• phosphazine
• Dexamethasone
• Cytosine

Topics

• 5-Methylcytosine
• Animals
• Antineoplastic Agents (pharmacology)
• Aziridines (pharmacology)
• Azirines (pharmacology)
• Cytosine (analogs & derivatives, metabolism)
• DNA, Neoplasm (metabolism)
• DNA, Single-Stranded (metabolism)
• Dexamethasone (pharmacology)
• Drug Synergism
• Male
• Rats
• Sarcoma, Experimental (metabolism)
• Viscosity