CASE PRESENTATION: The patient, a 50-year-old male, underwent a robotically assisted
colectomy for rectosigmoid
colon cancer, which was discovered when
hematochezia occurred. The patient received a diagnosis of pStage IIIb and was treated with four courses of CAPOX as
adjuvant chemotherapy starting at postoperative month 1. At postoperative month 4, contrast-enhanced computed tomography (CT) of the abdomen revealed a 20-mm, low-density area with heterogeneous internal structure in S6/7 of the liver. Abdominal ultrasound and
gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid-enhanced magnetic resonance imaging (EOB-MRI) findings led to a diagnosis of metastatic liver
tumor, for which a laparoscopic partial
hepatectomy was performed. The resected lesion was a dark reddish-brown nodule with indistinct margins that appeared to be continuous with the surrounding area. Histopathological analysis revealed severe, localized dilatation of the sinusoids and congestion consistent with the gross nodule. Based on these findings, localized
peliosis hepatis associated with
oxaliplatin-induced sinusoidal damage was diagnosed.
CONCLUSIONS: