Incidence of Nd:YAG laser capsulotomy following cataract surgery: a population-based nation-wide study - FreYAG1 study.

Abstract

RATIONALE:

Nd:YAG (neodymium:yttrium-aluminum-garnet) capsulotomy (Nd:YAG-caps) is the gold standard for the treatment of PCO (Posterior Capsule Opacification). There is a lack of real-world data about Nd:YAG-caps use.

PURPOSE:

This study's objectives were to estimate Nd:YAG-caps incidence in France, to describe the patient characteristics, and to analyze the time between surgeries and capsulotomies.

SETTING:

The study was based on data extracted from the EGB database, a 1/97th sample representative of the French population.

DESIGN:

observational, retrospective, cohort study using national claims data.

METHODS:

French adult patients who underwent Nd:YAG-caps between 2014 and 2017 were selected. Main outcomes were the number of patients and procedures performed and the risk factors associated with early Nd:YAG-caps.

RESULTS:

During the study period, Nd:YAG-caps were performed in 8,425 patients accounting for 10,774 procedures. The extrapolation to the French population led to estimate that 253.103 patients had Nd:YAG-caps, representing 312.103 procedures in 2017. The mean age at Nd:YAG-caps was 75.1 (± 10.2) years. About 36% of patients presented at least one ocular comorbidity. Nd:YAG-caps was performed within 2 years after surgery in 33.0% of patients and within one year in 9.8% of patients. Patients with Nd:YAG-caps within the first year (OR CI95 0.721 [0.673-0.772]) or in the first two years (OR CI95 0.721 [0.673-0.772]) were younger than patients with later Nd:YAG-caps and had a more frequent history of treated ocular diseases (OR 1.516 and 1.178, respectively).

CONCLUSIONS:

This study brought new real-world and large-scale data regarding Nd:YAG-caps use and gave an updated insight into the patients' characteristics.

• Authors: Antoine P Brézin, Antoine Labbe, Cédric Schweitzer, François Lignereux, Pascal Rozot, Mélanie Goguillot, Françoise Bugnard, Corinne Dot
• Journal: BMC ophthalmology (BMC Ophthalmol) Vol. 23 Issue 1 Pg. 417 (Oct 16 2023) ISSN: 1471-2415 [Electronic] England
• PMID: 37845645 (Publication Type: Observational Study, Journal Article)
• Copyright: © 2023. BioMed Central Ltd., part of Springer Nature.

Topics

• Adult
• Humans
• Middle Aged
• Aged
• Aged, 80 and over
• Lenses, Intraocular
• Lens Implantation, Intraocular
• Retrospective Studies
• Cohort Studies
• Lasers, Solid-State (therapeutic use)
• Incidence
• Lens Capsule, Crystalline (surgery)
• Postoperative Complications (etiology)
• Laser Therapy (adverse effects)
• Capsule Opacification (epidemiology, etiology, surgery)