Microrod crystals formed via Rhein-mediated mineralization.

Abstract

Herein, a Rhein-mineralized microrod crystal (H-RMM) with an ultra-high drug loading capacity was reported for anti-inflammation. Due to a dense crystal structure, the H-RMM achieved improved biocompatibility and sustained controlled release of Rhein. Also, the Rhein nanofibers released from H-RMM were favorable to be internalized by cells, leading to enhanced anti-inflammation effects.

• Authors: Jiaying Liu, Zhenyan Zhang, Yu Yan, Xiaonong Zhang, Chunsheng Xiao, Xuesi Chen
• Journal: Chemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 59 Issue 67 Pg. 10169-10172 (Aug 17 2023) ISSN: 1364-548X [Electronic] England
• PMID: 37534478 (Publication Type: Journal Article)

Chemical References

• rhein
• Anti-Inflammatory Agents
• Anthraquinones

Topics

• Anti-Inflammatory Agents
• Anthraquinones (pharmacology)