Emergency Posterior Decompression for Metastatic Spine Tumors in Octogenarians: Clinical Course and Prognostic Factors for Functional Outcomes.

Abstract

BACKGROUND:

This study aimed to describe the clinical outcome of metastatic epidural spinal cord compression in octogenarians with an acute onset of neurological illness who undergo laminectomy, further assess morbidity and mortality rates, and determine potential risk factors for a nonambulatory outcome.

METHODS:

This retrospective review of electronic medical records at a single institution was conducted between September 2005 and December 2020. Patient demographics, surgical characteristics, complications, hospital course, and 90-day mortality were collected.

RESULTS:

Thirty-four patients aged 80 years and older who posterior decompression via laminectomy were enrolled in the present study. The mean Charlson Comorbidity Index was >6 (9.2 ± 2.1). The thoracic spine was the most common site of metastasis. A potentially unstable spine, determined using the Spinal Instability Neoplastic Score, was identified in 79.4% of the cases. Preoperatively, the neurological condition and functional status exhibited a notable decline (mean Motor Score of the American Spinal Injury Association grading system, 78.2 ± 16.4; mean Karnofsky Performance Index, 47.8 ± 19.5). The Motor Score of the American Spinal Injury Association grading system and Karnofsky Performance Index scores improved significantly after surgery. Motor weakness and comorbidities were unique risk factors for the loss of ambulation.

CONCLUSIONS:

Emergent decompressive laminectomy in patients with acute onset of neurological decline and potentially unstable spines improved functional outcome at discharge. Age should not be a determinant of whether to perform surgery; surgery should be performed in older patients when indicated.

• Authors: Pavlina Lenga, Gelo Gülec, Awais Akbar Bajwa, Mohammed Issa, Karl Kiening, Andreas W Unterberg, Basem Ishak
• Journal: World neurosurgery (World Neurosurg) Vol. 175 Pg. e1315-e1323 (Jul 2023) ISSN: 1878-8769 [Electronic] United States
• PMID: 37164205 (Publication Type: Journal Article)
• Copyright: Copyright © 2023 Elsevier Inc. All rights reserved.

Topics

• Aged, 80 and over
• Humans
• Aged
• Prognosis
• Octogenarians
• Decompression, Surgical (adverse effects)
• Spinal Neoplasms (secondary)
• Spinal Cord Compression (etiology, surgery, pathology)
• Retrospective Studies
• Spinal Injuries (surgery)
• Disease Progression
• Treatment Outcome