[A Curatively Resected Case of Recto-Sigmoidal Cancer with Massive Bladder Invasion after Multimodal Therapy Including Chemotherapy].

Abstract

A 68-year-old male patient was referred to our hospital because of unfit to treat his recto-sigmoidal cancer massively invaded to bladder at the former hospital. During drug administration to treat heart failure, we could perform a transverse colostomy and initiated mFOLFOX plus Pmab. During chemotherapy, he improved malnutrition. After 7 courses, CT scan showed a marked reduction in tumor diameter, which was PR. Since his nutritional and heart status were improved, he underwent a high anterior resection with partial bladder resection. Pathological findings showed that a few cancer cells were remained at bladder and bowel wall. He was diagnosed as Stage Ⅱc. His postoperative course was almost uneventful. No symptom of recurrence has been observed at 9 months after surgery without adjuvant chemotherapy.

• Authors: Michi Ueno, Kazuhiko Yoshimatsu, Chiyuki Kageyama, Seiya Kinoshita, Shumei Mineta, Hironori Tanaka, Hisako Kubota, Masaharu Higashida, Yoshitomo Ito, Toshimasa Okada, Shunji Endo, Yoshinori Fujiwara, Tomio Ueno
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 50 Issue 4 Pg. 529-531 (Apr 2023) ISSN: 0385-0684 [Print] Japan
• PMID: 37066477 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Male
• Humans
• Aged
• Urinary Bladder
• Sigmoid Neoplasms (therapy)
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Chemotherapy, Adjuvant
• Cystectomy