Study of an antifungal medicine isavuconazole used in treatment of mold infections in China: A plain language summary.

Abstract

WHAT IS THIS SUMMARY ABOUT?:

Molds are types of fungus that can cause sickness and death. Mold infections are increasing in China. Until 2022, medicines that can effectively treat all mold infections were still lacking in China. This summary of a study originally published in the journal Infection and Drug Resistance. The study took place in China and tested a medicine called isavuconazole on mold samples to check if isavuconazole can be used to treat mold infections. Isavuconazole became available in China in January 2022 as a capsule (a hard gel-covered pill filled with a dose of medicine) and in June 2022 as an injection or a shot.

WHAT WERE THE RESULTS?:

Isavuconazole stopped the growth of most molds. Other medicines were needed at higher amounts to stop the growth of molds.

WHAT DO THE RESULTS OF THE STUDY MEAN?:

Isavuconazole is another option to treat mold infections in China.

• Authors: Ran Jing, Ian Morrissey, Meng Xiao, Tian-Shu Sun, Ge Zhang, Kang Wei, Da-Wen Guo, Jalal A Aram, Jeffrey Wang, Eric A Utt, Yao Wang, Ying-Chun Xu
• Journal: Future microbiology (Future Microbiol) Vol. 18 Pg. 87-91 (01 2023) ISSN: 1746-0921 [Electronic] England
• PMID: 36511165 (Publication Type: Journal Article, Review, Research Support, Non-U.S. Gov't)

Chemical References

• Antifungal Agents
• isavuconazole
• Nitriles

Topics

• Humans
• Antifungal Agents (pharmacology, therapeutic use)
• Aspergillosis (drug therapy)
• Mucormycosis (drug therapy)
• Fungi
• Nitriles (pharmacology, therapeutic use)
• China