Hyperammonaemia syndrome in disseminated Ureaplasma parvum infection.

Abstract

Hyperammonaemia syndrome secondary to Ureaplasma spp. infection is well documented in the post-lung transplant population. We report a case of a man in his fifties with hyperammonaemia syndrome secondary to disseminated Ureaplasma parvum infection. This occurred in the context of immunosuppression for chronic graft versus host disease and six years following an allogeneic stem cell transplant for diffuse large B-cell lymphoma. Following treatment of U. parvum septic arthritis with ciprofloxacin and doxycycline, the patient experienced a full neurological recovery, and continues on suppressive doxycycline therapy with no recurrence of symptoms to date.

• Authors: Nadiya Brell, Kristen Overton, Milton J Micallef, Siobhan Hurley
• Journal: BMJ case reports (BMJ Case Rep) Vol. 15 Issue 11 (Nov 09 2022) ISSN: 1757-790X [Electronic] England
• PMID: 36351675 (Publication Type: Case Reports, Journal Article)
• Copyright: © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Chemical References

• Doxycycline

Topics

• Male
• Humans
• Ureaplasma
• Doxycycline
• Hyperammonemia (etiology)
• Ureaplasma Infections (complications, diagnosis, drug therapy)
• Arthritis, Infectious
• Ureaplasma urealyticum