SURGICAL OUTCOMES OF VASOPROLIFERATIVE RETINAL TUMORS' REFRACTORY TO NONINVASIVE THERAPIES.

Abstract

PURPOSE:

To evaluate the outcomes of surgical treatment of refractory vasoproliferative retinal tumors (VPTs) and its complications.

METHODS:

Clinical charts of all patients diagnosed with VPTs who underwent surgical treatment from 2005 to 2020 were reviewed. Clinical features, surgical techniques, and outcomes were evaluated.

RESULTS:

From 25 eyes of 23 patients with VPTs, 17 (68%) eyes underwent surgical intervention to treat tumor activity and associated complications including epiretinal membrane (n = 10, 59%), retinal detachment (n = 8, 47%), and vitreous hemorrhage (n = 3, 18%). All eyes underwent pars plana vitrectomy with endolaser/cryotherapy to control tumor activity and to treat associated complications. Three cases required tumor resection. At the end of follow-up (mean 55.4 months, range 2-305 months), no eye presented tumor activity or retinal detachment after one or two surgeries. There was no epiretinal membrane recurrence. The mean baseline best-corrected visual acuity was 1.2 ± 0.7 logMAR, and the mean final best-corrected visual acuity was 0.7 ± 0.6 logMAR ( P < 0.05). The best-corrected visual acuity improved two or more lines in 12 (70.5%) eyes at the end of follow-up.

CONCLUSION:

In this series of patients with large active VPTs, surgical intervention allowed control of the tumor activity in all patients and provided overall satisfactory anatomic and functional outcomes.

• Authors: Virginia Mares, Carlos E Veloso, Jose S Pulido, Marcio B Nehemy
• Journal: Retina (Philadelphia, Pa.) (Retina) Vol. 42 Issue 9 Pg. 1772-1779 (09 01 2022) ISSN: 1539-2864 [Electronic] United States
• PMID: 35994586 (Publication Type: Journal Article)

Topics

• Epiretinal Membrane
• Humans
• Retinal Detachment (etiology, surgery)
• Retinal Neoplasms (diagnosis)
• Retrospective Studies
• Treatment Outcome
• Visual Acuity
• Vitrectomy (adverse effects)