Retinal Detachment (Retinal Detachments)

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4641 relevant articles (205 outcomes, 286 trials/studies) found for this Disease

Description: Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).

Also Known As:

Retinal Detachments; Detachment, Retinal; Detachments, Retinal; Retinal Pigment Epithelial Detachment

Relationship Network

Disease Context: Research Results

Eye Diseases: 1323

Retinal Diseases: 702

Retinal Detachment: 4641

Related Diseases

1.	Retinal Perforations
2.	Proliferative Vitreoretinopathy
3.	Cataract (Cataracts)
4.	Retinopathy of Prematurity (Retrolental Fibroplasia)
5.	Retinitis

Experts

1.	Flynn, H W: 6 articles (02/2008 - 01/2000)
2.	Hendrikse, Fred: 6 articles (01/2008 - 09/2002)
3.	La Heij, Ellen C: 6 articles (01/2008 - 09/2002)
4.	Chen, Muh-Shy: 5 articles (05/2008 - 03/2004)
5.	Shinoda, Kei: 5 articles (05/2008 - 02/2002)
6.	Arevalo, J F: 5 articles (02/2008 - 01/2000)
7.	Kessels, Alfons G H: 5 articles (04/2007 - 09/2002)
8.	Flynn, Harry W: 5 articles (06/2006 - 04/2003)
9.	Scott, Ingrid U: 5 articles (04/2005 - 04/2003)
10.	Zhang, Xi: 4 articles (09/2008 - 05/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Retinal Detachment:

1.	Retinaldehyde (Retinal)IBA 03/01/2004 - "RESULTS: The optical coherence tomography images showed a marked decrease in the retinal detachment in the first week after the injection with subsequent return to normal retinal thickness in all eyes. " 01/01/2003 - "In the remaining 4 patients whose VA could not be determined, improved behavioral patterns suggesting a successful surgical outcome were observed in 3 patients with bilateral retinal detachment, although in one of these patients only unilateral retinal reattachment was achieved. " 10/01/1998 - "CONCLUSION: Macula off retinal detachment, poor visual acuity plus or minus distortion, and multiple procedures for retinal reattachment are associated with a poor prognosis for restoration of binocular vision and a good outcome. " 03/01/1992 - "There was a statistically significantly greater migration with vitreous samples from group 3 than with group 1 (p less than 0.0001) but no significant correlation for migration with the age of patients, duration of retinal detachment, or number of retinal procedures undertaken. " 07/01/2002 - "In the early part of this century the success rate of retinal reattachment surgery was virtually nil and it was not until a better understanding of the pathophysiology of retinal detachment was gained that the success rate improved. " Order ALL the reference details at left...
2.	SiliconesIBA 07/01/1991 - "Because many complicated cases of retinal detachment can also be treated successfully with gas tamponade, silicone oil should remain the last step in retinal detachment surgery." 01/01/1990 - "Because many complicated cases of retinal detachment can also be treated successfully with gas tamponade, silicone oil should remain the last option in retinal detachment surgery." 01/01/1996 - "CONCLUSION: Silicone oil tamponade was effective for the treatment of retinal detachments with proliferative vitreo-retinopathy. " 04/01/2001 - "CONCLUSIONS: The systematic use of these surgical steps can be very useful in the management of retinal detachment relapses in eyes previously treated with silicone oil injection." 11/01/1998 - "CONCLUSION: Silicone oil injection is useful in the treatment of complicated retinal detachments. " Order ALL the reference details at left...
3.	ROPIBA 01/01/1987 - "The authors report their current techniques, which are based on improved understanding of the pathoanatomy and experience with more than 100 cases of retinal detachment in ROP treated with vitreous surgery." 01/01/2006 - "CONCLUSIONS: In the ETROP Study, the outcome of retinal detachment owing to ROP was generally poor. " 05/01/2009 - "Treatment of tractional partial retinal detachments involving the posterior pole (stage 4B ROP) is surgical. " 04/01/2008 - "METHODS: Retrospective analysis of 56 eyes (46 infants) with stage 4B ROP-related retinal detachment. " 03/01/2008 - "There was varying development of tractional retinal detachments in several of the eyes but the ROP component quieted in all cases. " Order ALL the reference details at left...
4.	Ganciclovir (Cytovene)FDA LinkGeneric 07/01/2007 - "CONCLUSIONS: In ARN patients whose conditions could not be controlled by systemic antivirus medicine treatment, early intravitreal injection of Ganciclovir can yield satisfactory therapeutic effects and better visual prognoses if applied before the occurrence of PVR or retinal detachment." 07/01/2007 - "The condition of 14 eyes deteriorated underwent intravitreal injection of Ganciclovir but without retinal detachment. " 04/01/2003 - "PURPOSE: To compare the rate of retinal detachment in a group of patients treated with intravitreal ganciclovir to the rate of retinal detachment in a group of patients treated with systemic ganciclovir. " 01/01/2001 - "RESULTS: No significant difference in the rate of retinal detachment was found between eyes treated with systemic therapy only and those treated with ganciclovir implants, whether used as primary therapy or subsequent to using systemic anti-CMV therapy. " 03/01/1998 - "The use of pneumatic retinopexy to delay surgical repair of a retinal detachment associated with the ganciclovir intraocular device." Order ALL the reference details at left...
5.	Fluorouracil (Carac)FDA LinkGeneric 01/01/1995 - "Devices containing 20% 5-FU (total of 1 mg) were 100% effective in prevention of tractional retinal detachment. " 01/01/1991 - "However, in eyes treated intravitreally with 5-Fluorouracil, retinal detachment or pucker appeared later, even in the second month suggesting routine follow-up of at least 2 months in future studies." 05/01/1993 - "No 5-FUR treated eye developed extensive tractional or combined tractional and rhegmatogenous retinal detachment compared with 33.3% (4 of 12) of 5-FU treated eyes and 80% (8 of 10) of control eyes (p < 0.001). " 01/01/1991 - "The rate of retinal detachment in fellow control eyes of rabbits following fibroblast administration is progressively lower with increased dose of 5-Fluorouracil in the test eyes. " 02/01/1984 - "5-fluorouracil: new applications in complicated retinal detachment for an established antimetabolite." Order ALL the reference details at left...
6.	densironIBA 10/01/2008 - "CONCLUSION: The recently developed heavy silicone oil tamponades are safe and effective tools for the use of complicated retinal detachments of the inferior fundus." 02/01/2006 - "INTRODUCTION: To evaluate the tolerance and efficacy of heavy silicone oil as internal tamponade for retinal detachment surgery. " 09/01/2009 - "The aim of this study was to evaluate the anatomic and functional outcome of complicated retinal detachment treated with vitreous surgery and heavy silicone oil (HSO) tamponade. " 11/01/2008 - "BACKGROUND: To report a retrospective non-comparative interventional study on the effectiveness and ocular tolerance of a heavy silicone oil tamponade (HSO, Densiron-68) for primary inferior rhegmatogenous retinal detachment (RRD). " 09/01/2007 - "CONCLUSIONS: According to the results of this study, vitreoretinal surgery with temporary heavy silicone oil tamponade appears to increase the anatomic success rates with minimal complication rate in cases with complicated retinal detachment and PVR." Order ALL the reference details at left...
7.	perfluorooctaneIBA 04/01/1995 - "CONCLUSION: Experience with perfluoro-N-octane has demonstrated its usefulness both diagnostically and therapeutically as an intraoperative tool and improved the anatomic and visual outcome for retinal detachment complicated by severe PVR." 02/01/2003 - "Perfluoro-octane internal tamponade when using a temporary keratoprosthesis during retinal detachment repair." 09/01/2002 - "A case report is presented of a patient with retained subretinal perfluoro-N-octane following retinal detachment repair for an ocular penetrating injury. " 07/15/1994 - "Management of complex retinal detachment with combined relaxing retinotomy and intravitreal perfluoro-n-octane injection." 01/01/1999 - "PURPOSE: This report describes the results of a prospective trial to evaluate the efficacy of pars plana vitrectomy (PPV) in conjunction with perfluoro-n-octane (PFO) as initial treatment of pseudophakic retinal detachment (RD) with no breaks diagnosed preoperatively. " Order ALL the reference details at left...
8.	perfluorophenanthreneIBA 06/01/2000 - "Safety and efficacy of the two perfluorocarbon liquids were evaluated in the subset of patients undergoing surgery for retinal detachment with PVR grade C or more, who had at least 6 months of postoperative follow-up (n = 46 in the Vitreon group and n = 55 in the PFO group). " 04/01/1994 - "Vitreon was found to be safe and effective in the repair of complicated retinal detachments. " 05/01/2000 - "PARTICIPANTS AND METHODS: Records of consecutive patients who underwent retinal detachment repair with intraoperative Perfluoron (n = 78) or Vitreon (n = 84) at the Bascom Palmer Eye Institute between November 1, 1991, and October 31, 1994, were retrospectively reviewed. " 01/01/1999 - "PURPOSE: To report the use of perfluoroperhydrophenanthrene (vitreon) for traumatic retinal detachment in children. " 01/01/1999 - "Management of traumatic retinal detachment with vitreon in children." Order ALL the reference details at left...
9.	Daunorubicin (Cerubidine)FDA LinkGeneric 01/01/1991 - "Daunorubicin (15 nmol) was effective in preventing retinal detachment in this model when injected simultaneously with the fibroblasts or in two doses (10 nmol followed by 5 nmol 4 h later) on the 3rd day after fibroblast injection. " 01/01/1983 - "We have studied the effect of daunomycin, a cytotoxic drug, in this model to determine a dose which would not be toxic to the retina but would be effective in preventing proliferation of the injected fibroblasts and eventual retinal detachment. " 01/01/1983 - "The results of this study demonstrate that daunomycin at a dose of 9 nmol per eye reduces the incidence of retinal detachment by over 50%. " 01/01/2004 - "The aim of the study was to evaluate the usefulness of daunorubicin, applied intravitreally during vitrectomy, as an antiproliferative factor stopping the vitreoretinal re-proliferations in eyes with rhegamatogenous retinal detachment complicated with PVR. " 01/01/2004 - "MATERIAL AND METHODS: Vitrectomy, with daunorubicin infusion (1 microg/ml), was performed in 6 eyes with rhegamatogenous retinal detachment and PVR. " Order ALL the reference details at left...
10.	ArgonIBA 02/01/1998 - "CONCLUSION: External argon laser choroidotomy appears to be an effective method of draining SRF in rhegmatogenous retinal detachments." 03/01/1975 - "This eye had a chronic retinal detachment which we could study adequately only after coreoplasty of the iris was carried out with the argon laser. " 10/01/1999 - "Incidence of retinal detachment is stable in France, in spite of argon laser prophylaxis. " 07/01/1998 - "RESULTS: One of the five patients had a peripheral rhegmatogenous retinal detachment that was limited by the argon laser row. " 07/01/1998 - "Argon laser coagulation for prevention of rhegmatogenic retinal detachment]" Order ALL the reference details at left...

Therapies and Procedures

1.	Vitrectomy 06/01/1994 - "The best results were obtained in patients receiving primary vitrectomy for complicated retinal detachment. " 09/01/1993 - "The spots were mainly noted in idiopathic cases and resolved completely in a few weeks, and the pattern was observed in macular pucker cases after retinal detachment surgery and persisted for a long time after vitrectomy." 03/01/2002 - "Visual outcome after vitrectomy is generally poor; however, cases that do not develop a retinal detachment may achieve good results." 09/01/1993 - "The retinal detachment was treated successfully with vitrectomy, drainage of the subretinal fluid, and gas tamponade. " 08/01/2006 - "PURPOSE: The aim of this study was to investigate the incidence of retinal detachment (RD) following pars plana vitrectomy and the efficacy of prophylactic means by cryoapplication central to the superior sclerotomies. " Order ALL the reference details at left...
2.	Scleral Buckling 12/01/1986 - "Scleral buckling techniques are effective in treating most eyes with rhegmatogenous retinal detachment, and usually the final visual result is limited only by possible preexisting macular damage due to the detachment. " 09/01/1999 - "CONCLUSIONS: We conclude that such a combined approach to primary pseudophakic and aphakic retinal detachments offers significant benefits to scleral buckling alone. " 06/01/1998 - "CONCLUSION: Pneumatic retinopexy for persistent retinal detachment, following scleral buckling, is effective in obtaining fast flattening of the retina and achieving good visual results." 11/01/1983 - "Prophylactic scleral buckling and/or an encircling procedure significantly decreased the incidence of postoperative retinal detachment." 11/01/2008 - "BACKGROUND AND OBJECTIVE: Scleral buckling is widely used for the treatment of rhegmatogenous retinal detachment. " Order ALL the reference details at left...
3.	Traction 12/01/2001 - "Retinal detachments in patients with smaller breaks and without vitreal traction or chronicity showed more significant reduction of subretinal fluid than did those patients with larger breaks and with vitreal traction or chronicity. " 01/01/1990 - "In one patient with a traction retinal detachment significant traction was relieved but the detachment failed to flatten completely. " 08/01/1983 - "A substantial reduction in the incidence of traction retinal detachment occurred and a significant improvement in visual prognosis was achieved." 02/01/1996 - "Amid 23 eyes which were vitrectomized for advanced traction retinal detachment, only 4 eyes improved to a postoperative visual acuity of > or = 0.02. " 11/01/1995 - "Appropriate case selection of eyes with associated central traction retinal detachment can result in improved visual field and central visual acuity. " Order ALL the reference details at left...
4.	Lasers (Laser) 12/01/1996 - "In retinal detachments due to giant tears the incidence of postoperative PVR was not statistically significantly greater in eyes managed with cryopexy (33.3%) than in eyes managed with laser retinopexy (15.6%). " 12/01/1991 - "In early stage, serous retinal detachment stage appeared and showed good outcome by laser treatment. " 07/01/2008 - "Furthermore, the study demonstrates that the aetiology of retinal detachment, the stage of PVR and the use of 360 degrees laser retinopexy have significant predictive value for visual outcome. " 01/01/1995 - "There are no studies to date reporting the use of the laser indirect ophthalmoscope coupled with scleral depression for treating retinal detachment. " 07/01/2009 - "Barrier laser did not reduce the risk of retinal detachment. " Order ALL the reference details at left...
5.	Light Coagulation 11/01/1989 - "Of the 3 remaining detachments, 2 eyes improved with additional photocoagulation, and 1 eye, which was not treated further, had a complete retinal detachment." 03/01/2009 - "Lesions containing a fibrovascular retinal pigment epithelial detachment tended to be larger (4.5 versus 3.8 Macular Photocoagulation Study Disc Areas), but this was not statistically significant. " 07/01/2008 - "Despite the adequate photocoagulation therapy, the proliferation progressed further, and partial tractional retinal detachment (TRD) occurred in the right eye, classified as stage 4A with plus disease. " 04/01/2004 - "RESULTS: In 10 of the 15 eyes, serous retinal detachment of sensory retina in the macula disappeared after photocoagulation of the feeder vessels. " 02/01/2002 - "The extraction of large clumps of exudates allowed us to replace serous retinal detachments and the photocoagulation of capillary anomalies. " Order ALL the reference details at left...

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