The development of a nomogram and the prognostic prediction value of patients with esophageal squamous cell carcinoma undergoing radical radiotherapy.

Abstract

AIM:

This study aimed to explore the role of the developed nomogram in the prognosis of esophageal squamous cell carcinoma (ESCC).

METHODS:

A total of 181 ESCC patients were randomly divided into a training cohort (n = 141) and a validation cohort (n = 40). Significant factors impacting overall survival (OS) were identified in the training set and integrated into the nomogram based on Cox proportional hazards regression.

RESULTS:

In the training cohort, the median OS in the high group (≥222) was 49.9 months and the median OS in the low group (<222) was 14.4 months. Multivariate analysis revealed that age, Karnofsky performance status score, tumor stage, chemotherapy, BMI, cervical esophageal carcinoma index and neutrophil to lymphocyte ratio were predictors of OS.

CONCLUSION:

The developed nomogram can effectively predict the survival prognosis of ESCC patients.

• Authors: Ling Xiao, Jiahua Lyu, Meihua Chen, Liu Wang, Jing Huang, Yajun Wei, Tao Li
• Journal: Future science OA (Future Sci OA) Vol. 8 Issue 3 Pg. FSO781 (Mar 2022) ISSN: 2056-5623 [Print] England
• PMID: 35251695 (Publication Type: Journal Article)
• Copyright: © 2022 The Authors.